Chapet Olivier, Kong Feng-Ming, Quint Leslie E, Chang Andrew C, Ten Haken Randall K, Eisbruch Avraham, Hayman James A
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA.
Int J Radiat Oncol Biol Phys. 2005 Sep 1;63(1):170-8. doi: 10.1016/j.ijrobp.2004.12.060.
Accurate delineation of the mediastinal and hilar lymph node regions is essential for a reproducible definition of target volumes used in conformal irradiation of non-small-cell lung cancer. The goal of this work was to generate a consensus to delineate these nodal regions based on definitions from the American Joint Committee on Cancer.
A dedicated thoracic radiologist, thoracic surgeon, medical physicist, and three radiation oncologists were gathered to generate a three-dimensional radiologic description for the mediastinal and hilar nodal regions on axial CT scans. This paper proposes an atlas of most of the lymph node stations described by Mountain and Dresler.
The CT boundaries of lymph node stations 1-2, 3, 4, 5, 6, 7, 8, 10-11 were defined on axial CT, along with image illustrations.
These CT-based illustrative definitions will provide guidelines for clinical practice and studies evaluating incidental radiation in radiotherapy. Studies are ongoing at the University of Michigan to measure quantitatively the incidental nodal radiation received by patients with non-small-cell lung cancer.
准确勾画纵隔和肺门淋巴结区域对于非小细胞肺癌适形放疗中靶区体积的可重复性定义至关重要。本研究的目的是根据美国癌症联合委员会的定义，就这些淋巴结区域的勾画达成共识。
召集一名专门的胸放射科医生、胸外科医生、医学物理学家和三名放射肿瘤学家，在轴向CT扫描上对纵隔和肺门淋巴结区域进行三维放射学描述。本文提出了一个由Mountain和Dresler描述的大部分淋巴结站的图谱。
在轴向CT上定义了淋巴结站1-2、3、4、5、6、7、8、10-11的CT边界，并配有图像说明。
这些基于CT的说明性定义将为临床实践和评估放疗中附带辐射的研究提供指导。密歇根大学正在进行研究，以定量测量非小细胞肺癌患者接受的附带淋巴结辐射。
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