在妊娠晚期服用抗抑郁药。我们应该如何向女性提供建议？
Taking antidepressants during late pregnancy. How should we advise women?
作者信息
Kalra S, Einarson A, Koren Gideon
机构信息
Hospital for Sick Children, Toronto, Ont.
出版信息
Can Fam Physician. 2005 Aug;51(8):1077-8.
QUESTION
In light of recent negative media attention to antidepressant use during late pregnancy, several of my patients have either discontinued or are considering discontinuing their antidepressant medications. How can I best counsel these patients on taking antidepressants during late pregnancy?
ANSWER
Antidepressant use during the third trimester has been associated occasionally with a transient neonatal withdrawal-like syndrome characterized by jitteriness, self-limiting respiratory difficulties, and problems with feeding. When counseling patients, the risk of these adverse effects must be weighed against the risks associated with untreated depression during late pregnancy. Abrupt discontinuation of psychotropic medications has been associated with both physical (eg, withdrawal) and psychological (eg, suicidal thoughts) symptoms.
问题
鉴于近期媒体对妊娠晚期使用抗抑郁药的负面关注，我的几位患者已经停药或正在考虑停药。我该如何最好地向这些患者提供关于在妊娠晚期服用抗抑郁药的咨询？
答案
妊娠晚期使用抗抑郁药偶尔会与一种短暂的新生儿戒断样综合征相关，其特征为易激惹、自限性呼吸困难和喂养问题。在为患者提供咨询时，必须权衡这些不良反应的风险与妊娠晚期未经治疗的抑郁症相关的风险。突然停用精神药物与身体（如戒断）和心理（如自杀念头）症状都有关。
Zotero 插件