Bousser M-G
Service de Neurologie, Hôpital Lariboisière, Paris, France.
Rev Neurol (Paris). 2005 Jul;161(6-7):700-2. doi: 10.1016/s0035-3787(05)85122-7.
Cerebrospinal fluid hypotension is a rare, incapacitating syndrome characterized by cerebrospinal fluid hypovolemia occurring in the absence of known dural tear. Severe orthostatic headache is the main symptom and clinical examination is usually normal. Magnetic resonance imaging shows the characteristic association of three signs: diffuse pachymeningeal gadolinium enhancement, sagging brain and bilateral subdural collections. Lumbar puncture is contraindicated. The single most effective treatment is lumbar epidural blood patch which cures over 50 percent of the patients and can be repeated in case of recurrence. The search for a dural tear is rarely necessary and surgical treatment is exceptionally required.
脑脊液低压是一种罕见的、使人衰弱的综合征,其特征是在无已知硬脑膜撕裂的情况下发生脑脊液容量减少。严重的体位性头痛是主要症状,临床检查通常正常。磁共振成像显示三种征象的特征性关联:弥漫性硬脑膜钆增强、脑下垂和双侧硬膜下积液。腰椎穿刺是禁忌的。最有效的单一治疗方法是腰椎硬膜外血贴,可治愈超过50%的患者,复发时可重复使用。很少需要寻找硬脑膜撕裂,极少需要手术治疗。