利用病毒血症献血者的随访样本评估西尼罗河病毒免疫球蛋白G亲和力作为近期感染指标的价值。
Utilization of follow-up specimens from viremic blood donors to assess the value of west nile virus immunoglobulin G avidity as an indicator of recent infection.
作者信息
Prince Harry E, Lapé-Nixon Mary, Busch Michael P, Tobler Leslie H, Foster Gregory A, Stramer Susan L
机构信息
Focus Diagnostics, Cypress, CA 90630, USA.
出版信息
Clin Diagn Lab Immunol. 2005 Sep;12(9):1123-6. doi: 10.1128/CDLI.12.9.1123-1126.2005.
Abstract
The value of West Nile virus immunoglobulin G avidity for distinguishing recent from past infection was investigated using 348 follow-up specimens from 170 viremic blood donors. Low avidity accurately indicated infection within the previous 4 months. However, due to rapid avidity maturation in some individuals, high avidity did not accurately indicate past infection.
摘要
利用来自170名病毒血症献血者的348份随访样本，研究了西尼罗河病毒免疫球蛋白G亲和力在区分近期感染与既往感染方面的价值。低亲和力准确表明在过去4个月内感染。然而，由于一些个体中亲和力迅速成熟，高亲和力并不能准确表明既往感染。
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