Artazkoz del Toro J J, Dalmau Galofré J, Faubel Serra M, Pons Rocher F, Vendrell Marqués J B
Servicio Orl, Hospital Dr. Peset, Valencia.
An Otorrinolaringol Ibero Am. 1992;19(3):283-90.
The onset of the bone radionecrosis is a relatively unusual problem which should be considered in the differential diagnosis of recurrences of irradiated tumors showing a high degree of aggressiveness. The AA. present a case report of a re-operated lower lip carcinoma which underwent further radiation therapy. A bony mandibular lesion was then observed, which led to the diagnosis of tumoral invasion at the mandible, and a partial mandibulectomy was then performed. The histopathological examination revealed a bone necrosis, probably due to radiotherapy. The clinical features and therapeutic management of mandibular osteoradionecrosis are commented.
骨放射性坏死的发生是一个相对不常见的问题,在鉴别诊断具有高度侵袭性的放疗后肿瘤复发时应予以考虑。作者报告了一例下唇癌再次手术并接受进一步放疗的病例。随后观察到下颌骨病变,诊断为下颌骨肿瘤侵犯,接着进行了部分下颌骨切除术。组织病理学检查显示为骨坏死,可能是放疗所致。文中对下颌骨放射性骨坏死的临床特征及治疗处理进行了评述。