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呼吸机相关性肺炎的预防与诊断:西班牙南部重症监护病房当前实践的调查

Prevention and diagnosis of ventilator-associated pneumonia: a survey on current practices in Southern Spanish ICUs.

作者信息

Sierra Rafael, Benítez Encarnación, León Cristóbal, Rello Jordi

机构信息

Intensive Care Unit, Puerta del Mar University Hospital, University of Cádiz, Spain.

出版信息

Chest. 2005 Sep;128(3):1667-73. doi: 10.1378/chest.128.3.1667.

Abstract

STUDY OBJECTIVES

To assess the implementation of selected ventilator-associated pneumonia (VAP) prevention strategies, and to learn how VAP is diagnosed in the ICUs of Southern Spain.

DESIGN

Multicentric survey.

SETTING

The ICUs of 32 hospitals of the public health-care system of Southern Spain.

PATIENTS OR PARTICIPANTS

Directors of ICUs.

INTERVENTIONS

None.

MEASUREMENTS AND RESULTS

Twenty-eight ICUs (87.5%) returned completed questionnaires. Ventilator circuits were changed every 72 h or longer in 75% of ICUs. Use of heat and moisture exchangers and open endotracheal suction systems were reported in 96% of ICUs. Subglottic secretion drainage was never used, and 57% of ICUs checked endotracheal tube cuff pressure at least daily. Semi-recumbent position was common (93%), and 67.5% of ICUs used frequently noninvasive ventilation. Continuous enteral feeding was reported in all ICUs. Sedative infusions were usually interrupted every day in 11% of ICUs. Seventy-five percent of ICUs had specific guidelines for antibiotic therapy of VAP, but rotation of antibiotics was uncommon (11%). Twenty-nine percent of ICUs diagnosed VAP without microbiological confirmation. The most used technique for microbiologic diagnosis was qualitative culture of endotracheal aspirates (42.8%). The centers with a larger structural complexity reported using VAP therapy guidelines more frequently than the smaller centers, but they did not utilized bronchoscopic techniques for diagnosing VAP.

CONCLUSIONS

Common prevention and diagnostic procedures in clinical practice, including large teaching institutions, significantly differed from evidence-based recommendations and reports by research groups of excellence. In addition, our study suggests that clinical practice for preventing and diagnosing VAP is variable and many opportunities exist to improve the care of patients receiving mechanical ventilation.

摘要

研究目的

评估所选呼吸机相关性肺炎(VAP)预防策略的实施情况,并了解西班牙南部重症监护病房(ICU)中VAP的诊断方法。

设计

多中心调查。

地点

西班牙南部公共卫生保健系统的32家医院的ICU。

患者或参与者

ICU主任。

干预措施

无。

测量与结果

28个ICU(87.5%)返回了完整问卷。75%的ICU每72小时或更长时间更换一次呼吸机回路。96%的ICU报告使用了热湿交换器和开放式气管内吸引系统。从未使用过声门下分泌物引流,57%的ICU至少每天检查气管导管套囊压力。半卧位很常见(93%),67.5%的ICU经常使用无创通气。所有ICU均报告采用持续肠内喂养。11%的ICU通常每天中断镇静剂输注。75%的ICU有VAP抗生素治疗的具体指南,但抗生素轮换并不常见(11%)。29%的ICU在没有微生物学确认的情况下诊断VAP。最常用的微生物学诊断技术是气管内吸出物的定性培养(42.8%)。结构复杂性较高的中心比规模较小的中心更频繁地报告使用VAP治疗指南,但它们未采用支气管镜技术诊断VAP。

结论

包括大型教学机构在内的临床实践中的常见预防和诊断程序与卓越研究小组的循证建议和报告存在显著差异。此外,我们的研究表明,预防和诊断VAP的临床实践存在差异,在改善接受机械通气患者的护理方面有很多机会。

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