Hussain Aziza M, Ismail Samina, Kamal Rehana S
Department of Anaesthesia, Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2005 Aug;55(8):348-50.
Pregnancy is poorly tolerated in patients with Eisenmenger syndrome (ES) with maternal mortality of 30-50%. Physiological changes of pregnancy decreases systemic vascular resistance that further aggravates the bi-directional or right to left shunt associated with ES. When it occurs with eclampsia, the morbidity and mortality are even higher. We report a case of 30 weeks pregnant woman with ES, who underwent emergency caesarian section because of pre-eclampsia. The intra-operative course was uneventful but she died on the second post-operative day. Post-operatively she was managed by the cardiologist in the coronary care unit. The probable cause being that she was over transfused, as the fluid status was not assessed by any invasive monitoring (like CVP). It was concluded that patients should be monitored closely in the post-operative period in the intensive care unit with complete invasive monitoring for up to a week to prevent factors resulting in worsening of the shunt (such as fluid balance) and thromboembolic phenomenon.
艾森曼格综合征(ES)患者对妊娠的耐受性较差,孕产妇死亡率为30%-50%。妊娠的生理变化会降低体循环血管阻力,这会进一步加重与ES相关的双向或右向左分流。当它与子痫同时发生时,发病率和死亡率更高。我们报告一例30周妊娠的ES患者,因先兆子痫接受了急诊剖宫产。术中过程顺利,但她在术后第二天死亡。术后她由心脏病专家在冠心病监护病房进行管理。可能的原因是她输血过量,因为没有通过任何有创监测(如中心静脉压)评估液体状态。得出的结论是,术后应在重症监护病房对患者进行密切监测,并进行长达一周的全面有创监测,以防止导致分流恶化的因素(如液体平衡)和血栓栓塞现象。