Strang J, Sheridan J
The National Addiction Centre, the Maudsley/Institute of Psychiatry, London, UK.
Drug Alcohol Rev. 1997 Mar;16(1):7-16. doi: 10.1080/09595239700186281.
Prescribing heroin in the treatment of addiction has been, until recently, an exclusively UK practice. However, despite international fascination with such prescribing, no recent report exists on the extent or nature of the practice. Furthermore, no data have ever previously been available on dispensing arrangements and geographical localization of heroin-prescribing to addicts. Data are presented on heroin prescriptions being dispensed to addicts in 1995, collected through the national survey of a 1 in 4 sample of the 10 616 community pharmacies in England and Wales. The 64 heroin prescriptions constituted only 1.7% of the 3846 prescriptions for opiates being issued to addicts by regarding community pharmacists, while methadone accounted for 96.0%. Heroin daily doses were more than three times higher than for methadone. Heroin was mainly prescribed in injectable form and, in contrast to methadone prescriptions, was mainly dispensed on a daily basis. Major regional variations in the extent of heroin-prescribing in the United Kingdom have been identified, with these variations appearing to relate to the practice of individual doctors rather than the nature of the local problem.
直到最近,在成瘾治疗中开具海洛因处方一直是英国独有的做法。然而,尽管国际上对这种处方很感兴趣,但最近没有关于这种做法的范围或性质的报告。此外,以前从未有过关于向成瘾者开具海洛因处方的配药安排和地理分布的数据。本文展示了1995年通过对英格兰和威尔士10616家社区药房四分之一样本进行全国性调查收集到的向成瘾者配给海洛因处方的数据。这64张海洛因处方仅占社区药剂师向成瘾者开具的3846张阿片类药物处方的1.7%,而美沙酮占96.0%。海洛因的每日剂量比美沙酮高出三倍多。海洛因主要以注射形式开具,与美沙酮处方不同的是,它主要按日配药。已确定英国海洛因处方开具范围存在主要的地区差异,这些差异似乎与个别医生的做法有关,而非当地问题的性质。