Hüttl T P, Hohle M, Wichmann M W, Jauch K-W, Meyer G
Department of Surgery, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 81366, Munich, Germany.
Surg Endosc. 2005 Dec;19(12):1579-87. doi: 10.1007/s00464-005-0163-0. Epub 2005 Oct 5.
This study aimed to evaluate the development and outcomes of laparoscopic antireflux surgery in Germany using a nationwide representative survey.
A written questionnaire including 34 detailed questions and 288 structured items about diagnostic and therapeutic approaches, number of procedures, complications, and mortality was sent to 546 randomly selected German surgeons (33% of the registered general surgeons) at the end of 2000.
The response rate was 72%, and a total of 2,540 antireflux procedures were reported. According to the survey, 81% of all procedures were performed laparoscopically, and 0.1% were performed thoracoscopically. As reported, 65% were total fundoplications, 31% were partial fundoplications, and 4% were other procedures. Of the surgeons who had experience with laparoscopic antireflux techniques (29%), 71% preferred a 5-trocar technique, and 91% used the Harmonic Scalpel for dissection. There were significant technical variations among the surgical procedures (e.g., use and size of the bougie, length of the wrap, additional gastropexy, fixation of the wrap). The overall complication rate for laparoscopic fundoplication was 7.7% (5.7% surgical and 2% nonsurgical complications), including rates of 0.6% for esophageal perforations and 0.6% for splenic lesions. The conversion rate was 2.9%; the reoperation rate was 1.6%; and the overall hospital mortality rate was 0.13%. The authors observed a striking learning curve difference in complication rates between hospitals performing fewer than 10 laparoscopic antireflux techniques annually and those performing more than 10 fundoplications per year (14% vs 5.1%, p < 0.001). Long-term dysphagia and interventions occasioned by dysphagia occurred significantly more often after total fundoplications than after partial fundoplications (6.6% vs 2.4%; p < 0.001). Similar findings were reported for Nissen versus floppy Nissen procedures. The overall failure rate, however, was similar for both groups (Nissen 8.7%; partial 9%, difference not significant).
Until now, no unique laparoscopic antireflux technique has been accepted, and a number of different antireflux procedures with numerous modifications have been reported. The morbidity and mortality rates reported in this article compare very well with those in the literature, and 1-year-follow-up results are promising.
本研究旨在通过一项全国代表性调查评估德国腹腔镜抗反流手术的发展情况及手术效果。
2000年末,向546名随机选取的德国外科医生(占注册普通外科医生的33%)发送了一份包含34个详细问题和288个关于诊断和治疗方法、手术例数、并发症及死亡率的结构化条目的书面调查问卷。
回复率为72%,共报告了2540例抗反流手术。根据调查,所有手术中81%为腹腔镜手术,0.1%为胸腔镜手术。报告显示,65%为全胃底折叠术,31%为部分胃底折叠术,4%为其他手术。有腹腔镜抗反流技术经验的外科医生中(29%),71%倾向于使用五孔技术,91%使用超声刀进行分离。手术操作存在显著的技术差异(例如,探条的使用和尺寸、胃底折叠的长度、附加胃固定术、胃底折叠的固定)。腹腔镜胃底折叠术的总体并发症发生率为7.7%(手术并发症5.7%,非手术并发症2%),其中食管穿孔率为0.6%,脾损伤率为0.6%。中转开腹率为2.9%;再次手术率为1.6%;总体医院死亡率为0.13%。作者观察到,每年进行少于10例腹腔镜抗反流手术的医院与每年进行超过10例胃底折叠术的医院在并发症发生率上存在显著的学习曲线差异(14%对5.1%,p<0.001)。全胃底折叠术后长期吞咽困难及因吞咽困难进行干预的情况显著多于部分胃底折叠术(6.6%对2.4%;p<0.001)。nissen术与松弛nissen术的情况也有类似发现。然而,两组的总体失败率相似(nissen术8.7%;部分胃底折叠术9%,差异无统计学意义)。
到目前为止,尚未有一种独特的腹腔镜抗反流技术被广泛接受,已报道了多种不同的抗反流手术及其众多改良方法。本文报道的发病率和死亡率与文献中的数据相比非常良好,1年随访结果很有前景。