Chandu Arun, MacIsaac Richard J, MacGregor Duncan P, Campbell Matthew C, Wilson Michael J, Bach Leon A
Department of ENT/Head and Neck Surgery, Austin Health, Studley Rd, Heidelberg 3084, Victoria, Australia.
Head Neck. 2005 Dec;27(12):1108-11. doi: 10.1002/hed.20287.
Mucormycosis is a rare fungal infection commonly affecting structures in the head and neck such as air sinuses, orbits, and the brain. Common predisposing factors include diabetes and immunosuppression. To date, only one case of mucormycosis involving the parotid gland has been reported, and this infection was associated with a fatal outcome.
We report a case of parotid gland mucormycosis in a 45-year-old woman with type 2 diabetes, who was successfully treated with a superficial parotidectomy and intravenous amphotericin B.
After initial surgical and antifungal therapy, the patient was left with a residual facial nerve palsy for which multiple sling procedures were performed. She is currently alive and well 6 years after the diagnosis of mucormycosis.
Mucormycosis of the parotid gland is a rare form of this often-fatal infection. In this case, infection remained isolated to the parotid gland and was diagnosed soon after presentation. The patient most likely survived because of the early diagnosis, successful surgical removal of all infected tissue, use of intravenous amphotericin therapy, and the aggressive management of comorbidities such as her diabetes.
毛霉菌病是一种罕见的真菌感染，通常影响头颈部结构，如鼻窦、眼眶和大脑。常见的诱发因素包括糖尿病和免疫抑制。迄今为止，仅报告过1例累及腮腺的毛霉菌病，该感染导致了致命后果。
我们报告1例45岁2型糖尿病女性腮腺毛霉菌病病例，患者接受了腮腺浅叶切除术和静脉注射两性霉素B治疗并获成功。
经过初始手术和抗真菌治疗后，患者遗留面神经麻痹，为此进行了多次悬吊手术。在诊断毛霉菌病6年后，她目前仍健在且情况良好。
腮腺毛霉菌病是这种常致命感染的一种罕见形式。在此病例中，感染仅局限于腮腺，且在就诊后不久即被诊断。患者得以存活很可能是由于早期诊断、成功手术切除所有感染组织、使用静脉两性霉素治疗以及积极处理如糖尿病等合并症。
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