前列腺癌继发急性尿潴留。初始经尿道前列腺切除术（TURP）是否有益？
Acute urinary retention secondary to carcinoma of the prostate. Is initial channel TURP beneficial?
作者信息
Thomas D J, Balaji V J, Coptcoat M J, Abercrombie G F
机构信息
Department of Urology, St Mary's Hospital, Portsmouth.
出版信息
J R Soc Med. 1992 Jun;85(6):318-9.
Over a 2-year period patients presenting with acute urinary retention secondary to locally advanced prostate carcinoma (stage T3/T4) were randomized to one of two treatments. Ten patients underwent channel transurethral resection of prostate (TURP) and bilateral orchidectomy, 12 patients underwent bilateral orchidectomy alone. Treatment by channel TURP and bilateral orchidectomy was complicated by difficulties in voiding in four patients, one requiring a further TURP. Ten of the 12 patients were voiding well one month following bilateral orchidectomy alone. Only two patients in this group required TURP. In patients with acute urinary retention secondary to prostate carcinoma, in whom hormonal manipulation is thought appropriate due to bulk of local tumour or metastatic disease, channel TURP may confer extra morbidity and therefore be held in reserve for those patients unable to void after hormonal manipulation.
在2年期间，将因局部晚期前列腺癌（T3/T4期）导致急性尿潴留的患者随机分为两种治疗方法之一。10例患者接受经尿道前列腺电切术（TURP）及双侧睾丸切除术，12例患者仅接受双侧睾丸切除术。经尿道前列腺电切术及双侧睾丸切除术治疗的4例患者出现排尿困难，其中1例需要再次进行经尿道前列腺电切术。仅接受双侧睾丸切除术的12例患者中有10例在术后1个月排尿良好。该组中只有2例患者需要进行经尿道前列腺电切术。对于因局部肿瘤体积大或存在转移性疾病而认为激素治疗合适的前列腺癌继发急性尿潴留患者，经尿道前列腺电切术可能会带来额外的发病率，因此应保留给激素治疗后仍无法排尿的患者。
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