Schmiege Sarah, Russo Nancy Felipe
Department of Psychology UCB 345, University of Colorado, Boulder, CO 80309-0345, USA.
BMJ. 2005 Dec 3;331(7528):1303. doi: 10.1136/bmj.38623.532384.55. Epub 2005 Oct 28.
To examine the outcomes of an unwanted first pregnancy (abortion v live delivery) and risk of depression and to explain discrepancies with previous research that used the same dataset.
Longitudinal cohort study.
Nationally representative sample of US men and women aged 14-24 in 1979.
1247 women in the US national longitudinal survey of youth who aborted or delivered an unwanted first pregnancy.
Clinical cut-off and continuous scores on a 1992 measure of the Center for Epidemiological Studies depression scale.
Terminating compared with delivering an unwanted first pregnancy was not directly related to risk of clinically significant depression (odds ratio 1.19, 95% confidence interval 0.85 to 1.66). No evidence was found of a relation between pregnancy outcome and depression in analyses of subgroups known to vary in under-reporting of abortion. In analyses of the characteristics of non-respondents, refusal to provide information on abortion did not explain the lack of detecting a relation between abortion and mental health. The abortion group had a significantly higher mean education and income and lower total family size, all of which were associated with a lower risk of depression.
Evidence that choosing to terminate rather than deliver an unwanted first pregnancy puts women at higher risk of depression is inconclusive. Discrepancies between current findings and those of previous research using the same dataset primarily reflect differences in coding of a first pregnancy.
研究意外首次怀孕的结局(流产与顺产)及抑郁风险,并解释与使用相同数据集的既往研究结果存在差异的原因。
纵向队列研究。
1979年美国14 - 24岁男性和女性的全国代表性样本。
美国全国青少年纵向调查中1247名意外首次怀孕后选择流产或顺产的女性。
1992年流行病学研究中心抑郁量表测量的临床临界值及连续评分。
与顺产意外首次怀孕相比,终止妊娠与临床显著抑郁风险无直接关联(比值比1.19,95%置信区间0.85至1.66)。在已知流产报告不足情况存在差异的亚组分析中,未发现妊娠结局与抑郁之间存在关联。在对未应答者特征的分析中,拒绝提供流产信息并不能解释为何未检测到流产与心理健康之间的关联。流产组的平均教育程度和收入显著更高,家庭总人口数更低,所有这些都与较低的抑郁风险相关。
关于选择终止而非顺产意外首次怀孕会使女性患抑郁症风险更高的证据尚无定论。当前研究结果与使用相同数据集的既往研究结果之间的差异主要反映了首次怀孕编码的不同。