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儿童甲癣:46例病例调查

Onychomycosis in children: a survey of 46 cases.

作者信息

Romano C, Papini M, Ghilardi A, Gianni C

机构信息

Department of Dermatology, University of Siena, Italy.

出版信息

Mycoses. 2005 Nov;48(6):430-7. doi: 10.1111/j.1439-0507.2005.01161.x.

Abstract

This is a retrospective study of the agents, clinical aspects, sources of infection and therapy of onychomycosis in children. In the period 1989-2000, we observed 46 consecutive children, until 16 years of age with onychomycosis (29 boys, 17 girls, mean age 10.8 years). Dermatophytes were isolated in 30 cases (Trichophyton rubrum in 22 cases, Trichophyton mentagrophytes in five, Epidermophyton floccosum in two and Trichophyton violaceum in one) and Candida spp. in 16, associated with Trichophyton rubrum in two. Moulds were isolated in three children (Fusarium oxysporum in one, Scopulariopsis brevicaulis in another and Aspergillus fumigatus associated with Trichophyton rubrum in a third). The commonest features were distal and distolateral subungual hyperkeratosis in dermatophyte infections (93%) and onychodystrophy and paronychia in Candida infections (56% and 50% respectively). Forty patients achieved clinical and mycological recovery. It is appropriate to suspect onychomycosis in children, perform microbiological diagnosis and undertake early treatment. An approach of this kind may help to prevent nail dystrophy and the spread of infection.

摘要

这是一项关于儿童甲癣的病原体、临床特征、感染源及治疗的回顾性研究。在1989年至2000年期间,我们观察了46例连续的16岁及以下甲癣患儿(29名男孩,17名女孩,平均年龄10.8岁)。分离出皮肤癣菌的有30例(红色毛癣菌22例、须癣毛癣菌5例、絮状表皮癣菌2例、紫色毛癣菌1例),分离出念珠菌属的有16例,其中2例与红色毛癣菌相关。有3名儿童分离出霉菌(1例尖孢镰刀菌、1例短帚霉、1例烟曲霉与红色毛癣菌相关)。最常见的特征是皮肤癣菌感染时远端和远侧甲下过度角化(93%),念珠菌感染时甲营养不良和甲沟炎(分别为56%和50%)。40例患者实现了临床和真菌学治愈。儿童出现甲癣时应怀疑该病,进行微生物学诊断并尽早治疗。这种方法可能有助于预防甲营养不良和感染传播。

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