Dózsa A, Károlyi Z S, Degrell P
Department of Dermatology Semmelweis Hospital, Miskolc, Hungary.
J Eur Acad Dermatol Venereol. 2005 Nov;19(6):725-8. doi: 10.1111/j.1468-3083.2005.01252.x.
Blepharochalasis is a rare disorder characterized by recurrent painless periorbital oedema, which leads to atrophy of the periorbital skin. Pathomechanism of the disease is probably immunological with a nearly complete loss of elastic fibres. The authors describe a 17-year-old woman, who was followed for 7 years. IgA deposits were found in the periorbital tissues, which confirm the immunological background of the condition. Electron microscopy results show that not only elastic but also collagen fibres were affected.
睑皮松弛症是一种罕见的疾病,其特征为反复发作的无痛性眶周水肿,进而导致眶周皮肤萎缩。该疾病的发病机制可能是免疫性的,弹性纤维几乎完全丧失。作者描述了一名随访7年的17岁女性。在眶周组织中发现了IgA沉积,这证实了该病的免疫背景。电子显微镜检查结果显示,不仅弹性纤维,胶原纤维也受到了影响。