Kumar Raj, Singh Vinita, Kumar Marakani V K
Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Indian J Pediatr. 2005 Oct;72(10):843-7. doi: 10.1007/BF02731111.
A retrospective analysis of 50 hydrocephalic children having a minimum follow-up of 6 months was carried out to see their etiology, clinical features, complications, incidence of shunt revisions, outcome and the variation from their Western counterparts.
Clinical features, image findings and treatment of all the cases were recorded from their discharge summaries. Record of shunt revision complications and outcome was maintained by the principal author. The data of all the cases were analyzed.
The age of children varied from 1 month to 12 yr (mean 2.2 yr). The most common etiology of hydrocephalus was aqueductal stenosis in 18 (36%) children. Post infective hydrocephalus, either of post-tubercular meningitis (TBM) or following bacterial meningitis, remained the cause in 15 children (30%). Congenital TORCH infection was responsible for 3 cases of hydrocephalus making infective etiology as the cause in 18 (36%) cases. Intra 4th ventricular neurocysticercus cyst caused blockade of CSF pathway in 2 children. 15 out of 50 children required shunt revision, either due to infection (8,16%) or shunt obstruction (7, 14%). Multiple shunt revisions were required in 2 children only. These revisions were required due to infection, obstruction or malfunction of the shunt.
Infective etiology is responsible for hydrocephalus in significant number of children (36%). The possibility of TORCH infection, as a cause of hydrocephalus should be considered even amongst the children of screened mothers during antenatal check-up. Pure intra 4th ventricular neurocysticercus cysts (without intraparenchymal cyst), though rare, can manifest with outlet obstruction. Incidence of shunt revision using Chhabra's medium pressure shunt is very high in children at an average follow up of 1.6 yr. Post infective hydrocephalus is a major cause of delayed milestones, contributing to mental retardation.
对50例脑积水患儿进行回顾性分析,这些患儿至少随访6个月,以观察其病因、临床特征、并发症、分流管修订发生率、结局以及与西方同行的差异。
从所有病例的出院小结中记录其临床特征、影像检查结果及治疗情况。由第一作者记录分流管修订的并发症及结局。对所有病例的数据进行分析。
患儿年龄从1个月至12岁不等(平均2.2岁)。脑积水最常见的病因是18例(36%)患儿的导水管狭窄。感染后脑积水,无论是结核性脑膜炎(TBM)后还是细菌性脑膜炎后,仍是15例患儿(30%)的病因。先天性TORCH感染导致3例脑积水,使感染性病因占18例(36%)。第四脑室内神经囊尾蚴囊肿导致2例患儿脑脊液通路阻塞。50例患儿中有15例需要进行分流管修订,原因是感染(8例,16%)或分流管阻塞(7例,14%)。仅2例患儿需要多次分流管修订。这些修订是由于感染、阻塞或分流管故障所致。
感染性病因导致相当数量的儿童脑积水(36%)。即使在产前检查中筛查过母亲的儿童中,也应考虑TORCH感染作为脑积水病因的可能性。单纯的第四脑室内神经囊尾蚴囊肿(无脑实质内囊肿)虽罕见,但可表现为出口阻塞。在平均随访1.6年的儿童中,使用Chhabra中压分流管进行分流管修订的发生率非常高。感染后脑积水是发育迟缓的主要原因,可导致智力低下。