1,4-二氮杂双环[2.2.2]辛烷催化α-卤代羰基化合物与二甲基乙炔二羧酸酯的反应：一种制备多取代呋喃和高官能化2H-吡喃的新方法。
DABCO-catalyzed reaction of alpha-halo carbonyl compounds with dimethyl acetylenedicarboxylate: a novel method for the preparation of polysubstituted furans and highly functionalized 2H-pyrans.
作者信息
Fan Mingjin, Yan Zeyi, Liu Weimin, Liang Yongmin
机构信息
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China.
出版信息
J Org Chem. 2005 Sep 30;70(20):8204-7. doi: 10.1021/jo050903g.
PMID:16277350
Abstract
[Chemical reaction: see text] Polysubstituted furans and highly functionalized 2H-pyrans were prepared in good yields by DABCO-catalyzed reactions of alpha-halo carbonyl compounds with dimethyl acetylenedicarboxylate (DMAD) at room temperature.
摘要
[化学反应：见正文] 通过1,4-二氮杂双环[2.2.2]辛烷（DABCO）催化的α-卤代羰基化合物与二甲基乙炔二羧酸酯（DMAD）在室温下的反应，以良好的产率制备了多取代呋喃和高度官能化的2H-吡喃。
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