Schönweiler R, Neumann A, Ptok M
Abteilung für Phoniatrie und Pädaudiologie (in der HNO-Klinik), Universitätsklinikum Schleswig-Holstein-Campus Lübeck.
HNO. 2005 Nov;53(11):983-94. doi: 10.1007/s00106-004-1187-9.
Auditory evoked responses to tone-pips in notched-noise provide frequency specific estimations of thresholds. Most often, test frequencies are 0.5-4 kHz. Thresholds are expected to match with a high degree to behavioral thresholds. However, only few studies are available containing data on stimulus and averaging parameters, especially at a test frequency of 0.25 kHz. In order to find "optimal" parameters for a widely used device (Nicolet Spirit Version 1.6), we designed five experiments on stimulus polarity (Exp.I), sweep frequency (Exp.II), stimulus duration (Exp.III), notched noise level (Exp.IV), and threshold estimation (Exp.V). The experiments also included a low test frequency of 0.25 kHz. These experiments were applied to 29 healthy volunteers (n=29, aged 20-41 years with normal hearing and no history of illness of the ear). We found that alternating stimulus polarity and a sweep frequency of 43.5/s evoked responses that were highest with respect to amplitudes (0.2-0.4 mV) and correlations (0.49-0.91). A novel finding of the study was that the highest amplitudes and correlations could be achieved if stimulus durations and notched-noise-levels were specifically adjusted to the test frequencies (stimulus durations 0.25 kHz: 4 ms, 0.5 Hz: 2 ms, 1-4 kHz: 1 ms, notched-noise-levels 0.25-0.5 Hz: +10 dB, 1-4 kHz: +/-0 dB). Deviations from behavioral thresholds did not exceed +/-5 dB in 93% of the measures. The results indicate that frequency specific auditory evoked responses provide reliable threshold estimations. Future experiments are required to confirm the threshold deviations for hard of hearing individuals.
在带通噪声中对短纯音的听觉诱发反应可提供频率特异性的阈值估计。测试频率通常为0.5 - 4千赫兹。预期阈值与行为阈值高度匹配。然而,仅有少数研究包含关于刺激和平均参数的数据,尤其是在0.25千赫兹的测试频率下。为了找到一种广泛使用的设备(Nicolet Spirit版本1.6)的“最佳”参数,我们设计了五个实验,分别针对刺激极性(实验一)、扫描频率(实验二)、刺激持续时间(实验三)、带通噪声水平(实验四)和阈值估计(实验五)。这些实验还包括了0.25千赫兹的低测试频率。这些实验应用于29名健康志愿者(n = 29,年龄在20 - 41岁之间,听力正常且无耳部疾病史)。我们发现,交替刺激极性和43.5/秒的扫描频率诱发的反应在幅度(0.2 - 0.4毫伏)和相关性(0.49 - 0.91)方面是最高的。该研究的一个新发现是,如果刺激持续时间和带通噪声水平根据测试频率进行特定调整(刺激持续时间:0.25千赫兹为4毫秒,0.5赫兹为2毫秒,1 - 4千赫兹为1毫秒;带通噪声水平:0.25 - 0.5赫兹为 +10分贝,1 - 4千赫兹为+/-0分贝),则可实现最高的幅度和相关性。在93%的测量中,与行为阈值的偏差不超过+/-5分贝。结果表明,频率特异性听觉诱发反应可提供可靠的阈值估计。未来需要进行实验以确认听力受损个体的阈值偏差。