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严重残疾是脊柱融合术的指征吗?使用碳纤维椎间融合器行后路腰椎椎间融合术后的长期疗效分析。

Is high level of disability an indication for spinal fusion? Analysis of long-term outcome after posterior lumbar interbody fusion using carbon fiber cages.

作者信息

Mofidi Ali, Sedhom Majed, O'Shea Kieran, Fogarty Esmonde E, Dowling Frank

机构信息

From the Elective Spinal Unit, Adelaide and Meath Hospital Incorporating the National Children's Hospital at Tallaght, Dublin, Republic of Ireland.

出版信息

J Spinal Disord Tech. 2005 Dec;18(6):479-84. doi: 10.1097/01.bsd.0000145481.92783.e7.

Abstract

OBJECTIVE

Posterior lumbar interbody fusion is a recognized procedure for the treatment of back pain associated with degenerative disc disease and segmental instability. It allows decompression of the spinal canal and circumferential fusion through a single posterior incision.

METHODS

Sixty-five consecutive patients who underwent posterior lumbar interbody fusion using carbon cages and pedicle fixation between 1993 and 2000 were recruited and contacted with a postal survey. Clinical outcome was assessed by the postoperative clinical findings and complications and the fusion rate, which was assessed using the scoring system described by Brantigan and Steffee. Functional outcome was measured by using improvement in the Oswestry Disability Index, return to work, and satisfaction with the surgical outcome. The determinants of functional relief were analyzed against the improvement in disability using multiple regression analysis.

RESULTS

The mean postoperative duration at the time of the study was 4.4 years. Overall radiologic fusion rate was 98%. There was a significant improvement in Oswestry Disability Index (P < 0.01). There was 84% satisfaction with the surgical procedure and 61% return to predisease activity level and full employment. We found preoperative level of disability to be the best determinant of functional recovery irrespective of age or the degree of psychological morbidity and litigation (P < 0.01).

CONCLUSION

The combination of posterior lumbar interbody fusion and posterior instrumented fusion is a safe and effective method of achieving circumferential segmental fusion. A direct relationship between preoperative level of disability and functional recovery suggests that disability should be measured preoperatively and spinal fusion should be performed to alleviate disability caused by degenerative spine.

摘要

目的

腰椎后路椎间融合术是治疗与椎间盘退变疾病及节段性不稳相关的背痛的一种公认术式。它可通过单一后路切口实现椎管减压及环形融合。

方法

选取1993年至2000年间连续接受使用碳笼和椎弓根固定的腰椎后路椎间融合术的65例患者,并通过邮寄调查问卷进行联系。临床结果通过术后临床表现、并发症及融合率进行评估,融合率采用Brantigan和Steffee描述的评分系统进行评估。功能结果通过Oswestry功能障碍指数的改善、恢复工作情况及对手术结果的满意度来衡量。使用多元回归分析针对功能障碍的改善情况分析功能缓解的决定因素。

结果

研究时的平均术后时间为4.4年。总体影像学融合率为98%。Oswestry功能障碍指数有显著改善(P < 0.01)。对手术的满意度为84%,61%的患者恢复到病前活动水平并实现全职工作。我们发现术前功能障碍水平是功能恢复的最佳决定因素,无论年龄或心理疾病及诉讼程度如何(P < 0.01)。

结论

腰椎后路椎间融合术与后路器械辅助融合术相结合是实现环形节段融合的一种安全有效的方法。术前功能障碍水平与功能恢复之间的直接关系表明,应在术前测量功能障碍情况,并应进行脊柱融合术以减轻由退行性脊柱引起的功能障碍。

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