Jitapunkul S, Pillay I, Ebrahim S
Department of Health Care of the Elderly, London Hospital Medical College.
Q J Med. 1992 Apr;83(300):307-14.
The prevalence, associated conditions and outcome of delirium were studied in a consecutive series of 184 patients admitted with acute illness to a department of health care of the elderly. Forty of these elderly subjects (22 per cent) met Diagnostic and Statistical Manual version 3 (revised) criteria for delirium. Screening for delirious patients using the abbreviated mental test on admission gave a high sensitivity (92 per cent). The conditions most commonly associated with delirium were infection and stroke. Onset of acute illness of less than 15 days, a reported history of dementia or recent confusion, and presence of a definite site of infection were much more likely in those with delirium. Serial use of the abbreviated mental test was a sensitive means of distinguishing delirious from other patients and may be useful in both the clinical and research setting. Delirious patients had more serious pre-existing disease than non-delirious patients. They had a higher number of admissions during the 2 years prior to the index admission, a higher mortality rate and a higher rate of transfer to long-stay care than other patients, but no difference in duration of admission. All acutely ill elderly people should undergo an abbreviated mental test on admission, and if abnormal, this should be repeated as it will aid detection of delirium.
对184名因急性疾病入住老年保健科的患者进行了连续研究,以探讨谵妄的患病率、相关情况及转归。其中40名老年患者(22%)符合《精神疾病诊断与统计手册》第3版(修订版)的谵妄诊断标准。入院时使用简易精神状态检查表对谵妄患者进行筛查,敏感性较高(92%)。与谵妄最常相关的情况是感染和中风。急性疾病发病时间少于15天、有痴呆或近期意识模糊的病史报告以及存在明确的感染部位,在谵妄患者中更为常见。连续使用简易精神状态检查表是区分谵妄患者与其他患者的一种敏感方法,在临床和研究环境中可能都有用。谵妄患者比非谵妄患者有更严重的基础疾病。他们在本次入院前2年内的住院次数更多,死亡率更高,转至长期护理机构的比例也高于其他患者,但住院时间无差异。所有急性病老年患者入院时均应接受简易精神状态检查表检查,若结果异常,应重复检查,因为这有助于谵妄的检测。