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主动脉性吞咽困难:主动脉食管瘘被忽视的症状。

Dysphagia aortica: a neglected symptom of aortoesophageal fistula.

作者信息

Contini S, Corrente V, Nervi G, Franzè A, Scarpignato C

机构信息

Department of Surgical Sciences, School of Medicine and Dentistry, University of Parma, Maggiore University Hospital, Via Gramsci 14, Italy.

出版信息

Dig Liver Dis. 2006 Jan;38(1):51-4. doi: 10.1016/j.dld.2005.03.015.

Abstract

Aortoesophageal fistula, secondary to thoracic aortic aneurysm, is an uncommon cause of gastrointestinal bleeding that is uniformly fatal without surgical intervention. Typical symptoms are midthoracic pain and/or dysphagia followed by a usually short, albeit unpredictable, symptom-free interval and by a 'herald' haemorrhage, which is observed in 80% of patients before fatal exsanguinations. Dysphagia is present in 45% of patients, sometimes for several weeks, before the first bleeding occurs. However, dysphagia aortica is rarely considered in the differential diagnosis of dysphagia and lack of awareness, as well as symptom's underevaluation, both contribute to a significant diagnostic and therapeutic delay. We present a case of a 77-year-old woman who died for a bleeding AEF consequent to a thoracic aortic aneurysm and whose main symptom during the past 2 months was dysphagia, which was not taken seriously into consideration by her general practitioner. This case report emphasises that primary care physicians should be alerted to evaluate carefully the alarming symptoms like dysphagia -- especially in elderly patients -- before life threatening complications occur, as they are the ones who could suspect early the diagnosis and make a proper referral.

摘要

继发于胸主动脉瘤的主动脉食管瘘是胃肠道出血的一种罕见原因,若无手术干预,通常会导致死亡。典型症状为胸中部疼痛和/或吞咽困难,随后会有一段通常较短但难以预测的无症状期,接着会出现“先兆”出血,80%的患者在致命性失血前会出现这种情况。45%的患者在首次出血前数周会出现吞咽困难。然而,在吞咽困难的鉴别诊断中,很少会考虑到主动脉性吞咽困难,意识不足以及对症状评估不足都会导致显著的诊断和治疗延迟。我们报告一例77岁女性病例,她因胸主动脉瘤导致的主动脉食管瘘出血死亡,在过去两个月里她的主要症状是吞咽困难,但她的全科医生并未认真考虑这一症状。本病例报告强调,基层医疗医生应提高警惕,在危及生命的并发症发生前,仔细评估吞咽困难等警示症状——尤其是老年患者——因为他们有可能早期怀疑诊断并进行适当转诊。

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