Loran David B, Hyde Brannon R, Zwischenberger Joseph B
Department of Surgery, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
Surg Clin North Am. 2005 Dec;85(6):1259-66, xi. doi: 10.1016/j.suc.2005.09.004.
Americans over age 65 represent the fastest growing segment of the United States population. As a result, the demographic landscape of America is changing. Knowledge of aged physiology is necessary to construct a risk-benefit analysis tailored for each patient to improve perioperative outcomes and lower the morbidity and mortality rates among the elderly. Benefit estimates should account for a patient's life expectancy and quality of life before and after surgery. With aging, baseline functions of almost every organ system undergo progressive decline resulting in a decreased physiologic reserve and ability to compensate for stress. Pain control, postoperative cognitive dysfunction, end-of-life issues, and realistic expectations after surgery are paramount issues throughout the perioperative period.
65岁以上的美国人是美国人口中增长最快的群体。因此,美国的人口结构正在发生变化。了解老年生理学对于为每位患者构建量身定制的风险效益分析至关重要,以改善围手术期结果并降低老年人的发病率和死亡率。效益评估应考虑患者手术前后的预期寿命和生活质量。随着年龄的增长,几乎每个器官系统的基线功能都会逐渐下降,导致生理储备减少和应对压力的能力下降。疼痛控制、术后认知功能障碍、临终问题以及手术后的现实期望是整个围手术期的首要问题。