原发性胃淋巴瘤与幽门螺杆菌感染合并胃淀粉样变性

Primary gastric lymphoma and Helicobacter pylori infection with gastric amyloidosis.

作者信息

Das Kshaunish, Ghoshal Uday C, Jain Manoj, Rastogi Archana, Tiwari Shridhar, Pandey Rakesh

机构信息

Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.

出版信息

Indian J Gastroenterol. 2005 Sep-Oct;24(5):220-2.

PMID:16361772

Abstract

Primary gastric lymphoma, an uncommon gastric tumor caused by infection with Helicobacter pylori, is rarely associated with gastric amyloidosis. Chronic bacterial infection is known to cause amyloidosis. We report a 53-year-old man who had an antral and duodenal mass with narrowing and ulceration on endoscopy and CT scan; endoscopic biopsy revealed gastric amyloidosis. Rapid urease test and serology for H. pylori were positive. Histology of resected specimen of distal stomach revealed primary gastric lymphoma, amyloid deposits and spiral organisms suggestive of H. pylori. Rectal biopsy was negative for amyloid. He remained well on follow-up after surgery and eradication of H. pylori.

摘要

原发性胃淋巴瘤是一种由幽门螺杆菌感染引起的罕见胃部肿瘤，很少与胃淀粉样变性相关。已知慢性细菌感染可导致淀粉样变性。我们报告一名53岁男性，其在内镜检查和CT扫描中发现胃窦和十二指肠有肿物，伴有狭窄和溃疡；内镜活检显示为胃淀粉样变性。幽门螺杆菌快速尿素酶试验和血清学检查均为阳性。远端胃切除标本的组织学检查显示为原发性胃淋巴瘤、淀粉样沉积物以及提示幽门螺杆菌的螺旋状微生物。直肠活检淀粉样变性为阴性。手术后，他在根除幽门螺杆菌后随访情况良好。