Cameron C M, Purdie D M, Kliewer E V, McClure R J
School of Medicine, Griffith University, Logan, Australia.
J Trauma. 2005 Sep;59(3):639-46.
The aim of the study was to quantify trauma-related mortality in injured adults over 10 years postinjury.
A population-based matched cohort study used linked administrative data from Manitoba, Canada, to identify an inception cohort (1988-1991) of hospitalized trauma cases (ICD-9-CM 800-959.9) aged 18-64 years (n = 18,210) and a matched noninjured comparison group (n = 18,210). Mortality outcomes were obtained by linking the two cohorts with the Manitoba Population Registry for a period of 10 years postinjury.
The adjusted all-cause mortality rate ratio (MRR) was 7.29 (95% CI 4.53-11.74) for the 60 days immediately postinjury. The MRRs ranged between 1.17 and 2.41 for the remainder of the 10 year follow-up period. The index injury was estimated to be responsible for 41% of all recorded deaths in the injured cohort.
Estimates of the total mortality burden, based on the early inpatient period alone, substantially underestimates the true burden from injury.
本研究的目的是对受伤成年患者伤后10年与创伤相关的死亡率进行量化。
一项基于人群的匹配队列研究，利用加拿大曼尼托巴省的关联行政数据，确定了一个起始队列（1988 - 1991年），其中包括18 - 64岁的住院创伤病例（国际疾病分类第九版临床修订本800 - 959.9）（n = 18210）以及一个匹配的未受伤对照组（n = 18210）。通过将这两个队列与曼尼托巴省人口登记处相链接，获取伤后10年的死亡率结果。
伤后即刻60天的调整全因死亡率比（MRR）为7.29（95%可信区间4.53 - 11.74）。在10年随访期的其余时间里，MRR在1.17至2.41之间。据估计，指数损伤导致受伤队列中所有记录死亡病例的41%。
仅基于早期住院期间对总死亡负担的估计，大大低估了创伤的真实负担。
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