Cassidy J David, Côté Pierre, Carroll Linda J, Kristman Vicki
Division of Outcomes and Population Health, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Spine (Phila Pa 1976). 2005 Dec 15;30(24):2817-23. doi: 10.1097/01.brs.0000190448.69091.53.
Population-based, prospective cohort.
To estimate incidence and course of severity-graded low back pain (LBP) episodes in adults.
Past studies report variable estimates that do not differentiate LBP severity.
An incidence cohort of 318 subjects free of LBP and a course cohort of 792 prevalent cases was formed from respondents to a mailed survey. Incident, recurrent, persistent, aggravated, improved, and resolved episodes were defined by the Chronic Pain Questionnaire. The follow-up at 6 and 12 months was 74% and 62%, respectfully. Annual estimates were age and sex standardized.
The cumulative incidence was 18.6% (95% confidence interval [CI], 14.2%-23.0%). Most LBP episodes were mild. Only 1.0% (95% CI, 0.0%-2.2%) developed intense and 0.4% (95% CI, 0.0%-1.0%) developed disabling LBP. Resolution occurred in 26.8% (95% CI, 23.7%-30.0%), and 40.2% (95% CI, 36.7%-43.8%) of episodes persisted. The severity of LBP increased for 14.2% (95% CI, 11.5%-16.8%) and improved for 36.1% (95% CI, 29.7%-42.2%). Of those that recovered, 28.7% (95% CI, 21.2%-36.2%)had a recurrence within 6months,and 82.4% of it was mild LBP. Younger subjects were less likely to have persistent LBP (incidence rate ratio, 0.88; 95% CI, 0.80-0.97) and more likely to have resolution (incidence rate ratio, 1.26; 95% CI, 1.02-1.56).
Most new and recurrent LBP episodes are mild. Less than one third of cases resolve annually, and more than 20% recur within 6 months. LBP episodes are more recurrent and persistent in older adults.
基于人群的前瞻性队列研究。
评估成年人中按严重程度分级的腰痛(LBP)发作的发生率及病程。
既往研究报告的估计值各不相同,且未区分LBP的严重程度。
通过邮寄调查问卷的受访者组成了一个由318名无LBP的受试者组成的发病队列和一个由792名现患病例组成的病程队列。慢性疼痛问卷定义了新发、复发、持续、加重、改善和缓解的发作情况。6个月和12个月时的随访率分别为74%和62%。年度估计值按年龄和性别进行了标准化。
累积发病率为18.6%(95%置信区间[CI],14.2%-23.0%)。大多数LBP发作是轻度的。只有1.0%(95%CI,0.0%-2.2%)发展为重度,0.4%(95%CI,0.0%-1.0%)发展为致残性LBP。26.8%(95%CI,23.7%-30.0%)的发作得到缓解,40.2%(95%CI,36.7%-43.8%)的发作持续存在。14.2%(95%CI,11.5%-16.8%)的LBP严重程度增加,36.1%(95%CI,29.7%-42.2%)的LBP严重程度改善。在恢复的患者中,28.7%(95%CI,21.2%-36.2%)在6个月内复发,其中82.4%为轻度LBP。较年轻的受试者发生持续性LBP的可能性较小(发病率比,0.88;95%CI,0.8