高效液相色谱法测定化妆品制剂中的α-生育酚烟酸酯

High-performance liquid chromatographic determination of alpha-tocopheryl nicotinate in cosmetic preparations.

作者信息

Baruffini A, De Lorenzi E, Gandini C, Kitsos M, Massolini G

机构信息

Department of Pharmaceutical Chemistry, Pavia, Italy.

出版信息

J Chromatogr. 1992 Feb 28;593(1-2):95-7. doi: 10.1016/0021-9673(92)80272-v.

DOI:10.1016/0021-9673(92)80272-v

PMID:1639917

Abstract

alpha-Tocopheryl nicotinate (alpha-TN) accelerates blood circulation and stimulates hair follicle cells, hence it is an active ingredient in a broad range of cosmetic products. A reversed-phase high-performance liquid chromatographic method was developed to determine alpha-TN in cosmetic preparations with alpha-tocopheryl acetate as internal standard. The method was found to be rapid, precise and specific.

摘要

α-生育酚烟酸酯（α-TN）可促进血液循环并刺激毛囊细胞，因此它是多种化妆品中的一种活性成分。建立了一种以α-生育酚醋酸酯为内标物测定化妆品制剂中α-TN的反相高效液相色谱法。该方法快速、准确且具有特异性。