Suppr超能文献

[从供体角度看活体肝移植:一项心身调查结果]

[Living donor liver transplantation from the perspective of the donor: results of a psychosomatic investigation].

作者信息

Walter Marc, Pascher Andreas, Jonas Sven, Danzer Gerhard, Frommer Jörg, Neuhaus Peter, Klapp Burghard F

机构信息

Medizinische Klinik mit Schwerpunkt Psychosomatik der Charité, Berlin, Germany.

出版信息

Z Psychosom Med Psychother. 2005;51(4):331-45. doi: 10.13109/zptm.2005.51.4.331.

Abstract

OBJECTIVES

Living donor liver transplantation (LDLT) has been gaining importance in the treatment of endstage liver disease in adults. Thus far, only few empirical studies have been published on the psychosocial situation of donors who are faced with the risk of medical complications after resection of the right hepatic lobe. The aims were to describe the clinical problems before and after transplantation and to contribute to the discussion of ethical issues based on empirical findings.

METHODS

In the present overview, the pre-/post-transplant and follow-up periods are characterized from a psychosocial point of view using actual psychosocial and medical findings in living donors of the right hepatic lobe.

RESULTS

Before LDLT, 11 % of potential donors were not recommended for the transplantation due to marked ambivalence about the operation. After donation 26 % of donors showed high values for anxious depression and physical complaints despite low rates of surgical complications.

CONCLUSIONS

For clinical psychosomatic evaluations of potential donors it is important to provide donors an opportunity to report any misgivings and anxieties as openly as possible. The psychosocial impairment and physical complaints of some donors after transplantation are yet not clearly understood. More psychosocial studies in this field will be necessary to investigate ethical questions and to develop criteria for an evidence-based medical care of living donors.

摘要

目的

活体肝移植(LDLT)在成人终末期肝病的治疗中日益重要。迄今为止,关于右肝叶切除术后面临医疗并发症风险的供体的社会心理状况,仅有少数实证研究发表。目的是描述移植前后的临床问题,并基于实证研究结果为伦理问题的讨论提供参考。

方法

在本综述中,从社会心理角度,利用右肝叶活体供体的实际社会心理和医学研究结果,对移植前后及随访阶段进行描述。

结果

在活体肝移植前,11%的潜在供体因对手术存在明显矛盾心理而未被推荐进行移植。捐献后,尽管手术并发症发生率较低,但26%的供体表现出焦虑抑郁和身体不适的高分值。

结论

对于潜在供体的临床身心评估,重要的是为供体提供机会,让他们尽可能公开地报告任何疑虑和焦虑。目前尚不清楚一些供体在移植后的社会心理损害和身体不适情况。该领域需要更多的社会心理研究,以调查伦理问题,并制定基于证据的活体供体医疗护理标准。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验