Total synthesis of UCS1025A.
作者信息
Lambert Tristan H, Danishefsky Samuel J
机构信息
Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, New York, New York 10021, USA.
出版信息
J Am Chem Soc. 2006 Jan 18;128(2):426-7. doi: 10.1021/ja0574567.
PMID:16402826
Abstract
The enantioselective total synthesis of the telomerase inhibitor UCS1025A has been accomplished. The key transformation involves a remarkable boron Reformatsky coupling of iodolactone 13 and aldehyde 17.
摘要
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