蛛网膜下腔出血后的脑血管反应性与血管痉挛：一项初步研究。

Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study.

作者信息

Frontera J A, Rundek T, Schmidt J M, Claassen J, Parra A, Wartenberg K E, Temes R E, Mayer S A, Mohr J P, Marshall R S

机构信息

Division of Stroke and Neurocritical Care, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

出版信息

Neurology. 2006 Mar 14;66(5):727-9. doi: 10.1212/01.wnl.0000200777.96896.3d. Epub 2006 Jan 25.

DOI:10.1212/01.wnl.0000200777.96896.3d

PMID:16436650

Abstract

The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2R and in none of 6 patients with preserved reactivity (p = 0.011). Abnormal CO2R preceded the onset of vasospasm in 7 of 9 patients. Abnormal standard TCD testing was not associated with vasospasm.

摘要

作者对20例动脉瘤性蛛网膜下腔出血患者进行了连续经颅多普勒（TCD）和二氧化碳反应性（CO2R）测试，以确定脑血管反应性受损是否与症状性血管痉挛相关。14例CO2R异常的患者中有9例发生了症状性血管痉挛，而6例反应性正常的患者均未发生（p = 0.011）。9例患者中有7例在血管痉挛发作前CO2R异常。标准TCD测试异常与血管痉挛无关。