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黑色素瘤筛查诊所:我们是检测出了更多的黑色素瘤,还是让忧心忡忡的健康人群安心了?

Melanoma screening clinics: are we detecting more melanomas or reassuring the worried well?

作者信息

Weatherhead S C, Lawrence C M

机构信息

Department of Dermatology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK.

出版信息

Br J Dermatol. 2006 Mar;154(3):539-41. doi: 10.1111/j.1365-2133.2005.07108.x.

Abstract

BACKGROUND

Melanoma screening clinics (MSCs) have been set up in the U.K. to help allay public anxiety about potential skin cancers, and to permit the early detection of thin melanomas, thus improving prognosis. Public health campaigns have led to increased awareness of melanoma and increased numbers of referrals to MSCs.

OBJECTIVES

To determine whether the MSC has had an impact on the number and thickness of melanomas detected over the past 8 years.

METHODS

Data was analysed retrospectively for all patients attending the MSC since it was set up in 1997, until the end of 2004. We categorized patients with melanoma according to Breslow thickness, examined trends in referral to the clinic and analysed changes in the proportion of patients with a new diagnosis of melanoma.

RESULTS

There were 15 970 patients who attended for screening; 403 primary invasive melanomas were detected, and 190 in situ melanomas. The number of new patients seen each year increased by over 230%, although the proportion of patients with melanoma detected declined. The Breslow thickness did not change over time.

CONCLUSIONS

Our experience suggests that public awareness has increased and that the general practitioner threshold for referral has fallen but there has been no reduction in the thickness of those melanomas diagnosed.

摘要

背景

英国已设立黑色素瘤筛查诊所(MSC),以缓解公众对潜在皮肤癌的焦虑,并实现对薄型黑色素瘤的早期检测,从而改善预后。公共卫生运动提高了人们对黑色素瘤的认识,转诊至MSC的人数也有所增加。

目的

确定在过去8年中,MSC对所检测到的黑色素瘤的数量和厚度是否产生了影响。

方法

对自1997年MSC设立至2004年底期间就诊的所有患者的数据进行回顾性分析。我们根据Breslow厚度对黑色素瘤患者进行分类,研究转诊至该诊所的趋势,并分析新诊断为黑色素瘤的患者比例的变化。

结果

共有15970名患者前来筛查;检测到403例原发性侵袭性黑色素瘤和190例原位黑色素瘤。每年就诊的新患者数量增加了230%以上,尽管检测到的黑色素瘤患者比例有所下降。Breslow厚度并未随时间变化。

结论

我们的经验表明,公众意识有所提高,全科医生的转诊门槛降低,但所诊断出的黑色素瘤的厚度并未减小。

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