化疗在唾液腺恶性肿瘤单纯治疗与综合治疗中的当前作用。
Current role of chemotherapy in exclusive and integrated treatment of malignant tumours of salivary glands.
作者信息
Cortesina G, Airoldi M, Palonta F
机构信息
Second ORL Clinic, University of Turin, San Giovanni Antica Sede Hospital, Turin, Italy.
出版信息
Acta Otorhinolaryngol Ital. 2005 Jun;25(3):179-81.
In the management of salivary glands carcinomas, surgery is the treatment of choice. Post-operative radiotherapy is indicated in cases with high risk of loco-regional relapse. Radiotherapy is also standard treatment in cases that are inoperable at onset. Chemotherapy plays a palliative role. Today, the integration between radiotherapy and chemotherapy, which provides increased local control, represents a significant step forward. This integration is important since 5-year survival in tumours with high grade histology is approximately 50%. Overall incidence of metastases is approximately 25%. Primary locations of metastases are lungs, liver, bone, central nervous system and other organs. In cases of metastatic disease, chemotherapy plays only a palliative role.
在唾液腺癌的治疗中，手术是首选的治疗方法。对于局部区域复发风险高的病例，术后放疗是必要的。放疗也是初发时无法手术的病例的标准治疗方法。化疗起姑息作用。如今，放疗与化疗的联合应用提高了局部控制率，是向前迈出的重要一步。这种联合很重要，因为高分级组织学肿瘤的5年生存率约为50%。转移的总体发生率约为25%。转移的主要部位是肺、肝、骨、中枢神经系统和其他器官。在转移性疾病的病例中，化疗仅起姑息作用。
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