Nandan Ratheesh K, Sivapathasundharam B, Sivakumar G
Department of Oral and Maxillofacial Pathology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamilnadu, India.
Indian J Dent Res. 2005 Jul-Sep;16(3):77-82.
To evaluate oral manifestations in patients with renal diseases and to correlate blood and salivary urea levels in patients undergoing haemodialysis and kidney transplant.
Study group subjects were selected from patients undergoing hemodialysis and patients who had underwent kidney transplant. Adequate history was recorded. All the groups were examined extra orally and intra orally and findings were recorded. SAMPLE COLLECTION: Venous blood was collected from the antecubital fossa in control group. In patients with renal disease undergoing dialysis, blood was collectedjust prior to the dialysis. Renal transplant patients' blood samples were collected during review visit. Unstimulated saliva was collected and submitted to the laboratory immediately for urea examination by an automated analyzer.
Extra oral manifestations like swollen face, pale skin, pedal edema, and bruises on the skin, nausea and vomiting in nearly 50% of the patiens, and oral manifestations like uraemic odour, dry mouth, and altered taste sensation were noted. There was a correlation between blood urea and salivary urea concentration in patients under going hemodialysis and kidney transplant.
Saliva can be used as a non-invasive diagnostic tool.
评估肾脏疾病患者的口腔表现，并关联接受血液透析和肾移植患者的血液及唾液尿素水平。
研究组受试者选自接受血液透析的患者和已接受肾移植的患者。记录详细病史。对所有组进行口腔外和口腔内检查，并记录检查结果。样本采集：对照组从肘前窝采集静脉血。在接受透析的肾脏疾病患者中，于透析前采集血液。肾移植患者的血样在复诊时采集。收集非刺激性唾液，并立即送交实验室，通过自动分析仪进行尿素检测。
注意到近50%的患者有面部肿胀、皮肤苍白、足部水肿、皮肤瘀伤、恶心和呕吐等口腔外表现，以及尿毒症气味、口干和味觉改变等口腔表现。接受血液透析和肾移植的患者，其血液尿素与唾液尿素浓度之间存在相关性。
唾液可作为一种非侵入性诊断工具。
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