Peirce Jessica M, Petry Nancy M, Stitzer Maxine L, Blaine Jack, Kellogg Scott, Satterfield Frank, Schwartz Marion, Krasnansky Joe, Pencer Eileen, Silva-Vazquez Lolita, Kirby Kimberly C, Royer-Malvestuto Charlotte, Roll John M, Cohen Allan, Copersino Marc L, Kolodner Ken, Li Rui
Mid Atlantic Node, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Arch Gen Psychiatry. 2006 Feb;63(2):201-8. doi: 10.1001/archpsyc.63.2.201.
Contingency management interventions that provide tangible incentives based on objective indicators of drug abstinence have improved treatment outcomes of substance abusers, but have not been widely implemented in community drug abuse treatment settings.
To compare outcomes achieved when a lower-cost prize-based contingency management treatment is added to usual care in community methadone hydrochloride maintenance treatment settings.
Random assignment to usual care with (n = 198) or without (n = 190) abstinence incentives during a 12-week trial.
Six community-based methadone maintenance drug abuse treatment clinics in locations across the United States.
Three hundred eighty-eight stimulant-abusing patients enrolled in methadone maintenance programs for at least 1 month and no more than 3 years.
Participants submitting stimulant- and alcohol-negative samples earned draws for a chance to win prizes; the number of draws earned increased with continuous abstinence time.
Total number of stimulant- and alcohol-negative samples provided, percentage of stimulant- and alcohol-negative samples provided, longest duration of abstinence, retention, and counseling attendance.
Submission of stimulant- and alcohol-negative samples was twice as likely for incentive as for usual care group participants (odds ratio, 1.98; 95% confidence interval, 1.42-2.77). Achieving 4 or more, 8 or more, and 12 weeks of continuous abstinence was approximately 3, 9, and 11 times more likely, respectively, for incentive vs usual care participants. Groups did not differ on study retention or counseling attendance. The average cost of prizes was 120 dollars per participant.
An abstinence incentive approach that paid 120 dollars in prizes per participant effectively increased stimulant abstinence in community-based methadone maintenance treatment clinics.
基于药物戒断客观指标提供切实奖励的应急管理干预措施改善了药物滥用者的治疗效果,但尚未在社区药物滥用治疗环境中广泛实施。
比较在社区美沙酮盐酸维持治疗环境中,在常规治疗基础上增加低成本基于奖励的应急管理治疗时所取得的效果。
在为期12周的试验中,随机分配为接受(n = 198)或不接受(n = 190)戒断奖励的常规治疗。
美国各地的6个社区美沙酮维持药物滥用治疗诊所。
388名参加美沙酮维持项目至少1个月且不超过3年的兴奋剂滥用患者。
提交兴奋剂和酒精检测呈阴性样本的参与者可获得抽奖机会以赢取奖品;随着持续戒断时间的延长,获得的抽奖次数增加。
提供的兴奋剂和酒精检测呈阴性样本总数、提供的兴奋剂和酒精检测呈阴性样本的百分比、最长戒断持续时间、留存率和咨询出勤率。
与常规治疗组参与者相比,奖励组参与者提交兴奋剂和酒精检测呈阴性样本的可能性高出两倍(优势比,1.98;95%置信区间,1.42 - 2.77)。与常规治疗参与者相比,奖励组参与者实现连续4周或更长时间、8周或更长时间以及12周或更长时间戒断的可能性分别高出约3倍、9倍和11倍。两组在研究留存率或咨询出勤率方面无差异。奖品的平均成本为每位参与者120美元。
每位参与者支付120美元奖品的戒断奖励方法有效地提高了社区美沙酮维持治疗诊所的兴奋剂戒断率。