Trelles Mario A, Martín-Vázquez Manuel, Trelles Oswaldo R, Mordon Serge R
Instituto Médico Vilafortuny/Fundación Antoni de Gimbernat, Cambrils, Tarragona, Spain.
Lasers Surg Med. 2006 Mar;38(3):185-95. doi: 10.1002/lsm.20280.
Effective laser treatment of leg veins remains a major challenge. The present study examined the safety and efficacy of a new technology for leg vein treatment combining 900 nm diode laser with radiofrequency (RF) current.
STUDY DESIGN/MATERIALS AND METHODS: Forty patients, skin types II-IV, received a maximum of three treatments on 1-4 mm leg veins at 2-week intervals with a 900 nm diode laser (250 millisecond exposure time, average fluence 60 J/cm2) and RF (energy 100 J/cm3). Results were assessed after each treatment and at 2 and 6 months after the final session. Patients rated their satisfaction with the clinical outcome on a five-item scale. Clinician and computer analysis of the clinical photography was also performed, in addition to histological assessment.
One or two sessions were required in the majority of patients. Shortly after treatment, histology revealed contracted vessels with perivascular edema. Side effects were extremely rare. The clinician 2- and 6-month assessments showed that 70% and 82.5% of subjects, respectively, achieved over 50% clearance, with patient and computer assessments lower and slightly higher, respectively. Treatments showed greater efficacy on thicker vessels and in the darker skin types.
The success of the treatment, minimal side effects, and patient comfort suggest that this combination is an effective, safe technique for leg vein treatment. When compared to previous studies using diode laser alone, the very low fluence needed to achieve vessel clearance emphasizes the role of RF energy.
有效地利用激光治疗腿部静脉仍是一项重大挑战。本研究探讨了一种将900纳米二极管激光与射频电流相结合用于治疗腿部静脉的新技术的安全性和有效性。
研究设计/材料与方法:40例皮肤类型为II-IV型的患者,对其1-4毫米的腿部静脉接受了最多三次治疗,治疗间隔为2周,采用900纳米二极管激光(曝光时间250毫秒,平均能量密度60 J/cm²)和射频(能量100 J/cm³)。每次治疗后以及最后一次治疗后的2个月和6个月对结果进行评估。患者通过一个五项量表对临床结果的满意度进行评分。除了组织学评估外,还对临床照片进行了临床医生和计算机分析。
大多数患者需要进行一或两次治疗。治疗后不久,组织学显示血管收缩伴有血管周围水肿。副作用极为罕见。临床医生在2个月和6个月时的评估显示,分别有70%和82.5%的受试者血管清除率超过50%,患者评估结果较低,计算机评估结果略高。治疗对较粗的血管和肤色较深的皮肤类型显示出更大的疗效。
治疗的成功、最小的副作用以及患者的舒适度表明,这种联合治疗是一种有效、安全的腿部静脉治疗技术。与之前单独使用二极管激光的研究相比,实现血管清除所需的极低能量密度强调了射频能量的作用。