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病毒性脑膜炎

Viral meningitis.

作者信息

Chadwick David R

机构信息

Department of Infection & Travel Medicine, The James Cook University Hospital, Middlesbrough TS4 3BW, UK.

出版信息

Br Med Bull. 2006 Feb 10;75-76:1-14. doi: 10.1093/bmb/ldh057. Print 2005.

Abstract

Viruses probably account for most cases of acute meningitis. Viral meningitis is often assumed to be a largely benign disease. For the commonest pathogens causing meningitis, enteroviruses, this is usually the case; however, for many of the other pathogens causing viral meningitis, and for common pathogens in the immunocompromised or infants, viral meningitis is frequently associated with substantial neurological complications and a significant mortality. Diagnostic methods for rapid and accurate identification of pathogens have improved over recent years, permitting more precise and earlier diagnoses. There have been fewer developments in therapies for viral meningitis, and there remain no effective therapies for most pathogens, emphasising the importance of prevention and early diagnosis. This review focuses on the presentation, diagnosis and management of viral meningitis and also covers the prevention of meningitis for pathogens where effective vaccines are available.

摘要

病毒可能是大多数急性脑膜炎病例的病因。病毒性脑膜炎通常被认为是一种基本良性的疾病。对于引起脑膜炎最常见的病原体肠道病毒来说,情况通常如此;然而,对于许多其他引起病毒性脑膜炎的病原体,以及免疫功能低下者或婴儿中的常见病原体而言,病毒性脑膜炎常常伴有严重的神经系统并发症和较高的死亡率。近年来,快速准确鉴定病原体的诊断方法有所改进,从而能够进行更精确、更早的诊断。病毒性脑膜炎治疗方法的进展较少,对于大多数病原体仍然没有有效的治疗方法,这凸显了预防和早期诊断的重要性。本综述重点关注病毒性脑膜炎的临床表现、诊断和管理,还涵盖了针对有有效疫苗的病原体预防脑膜炎的内容。

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