血友病患者致命的中心静脉导管相关感染

Fatal central venous catheter-related infection in haemophilia.

作者信息

Crary S E, Buchanan G R, Journeycake J M

机构信息

Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9063, USA.

出版信息

Haemophilia. 2006 Mar;12(2):183-6. doi: 10.1111/j.1365-2516.2006.01176.x.

DOI:10.1111/j.1365-2516.2006.01176.x

PMID:16476095

Abstract

Central venous catheters (CVC) are frequently used in children with haemophilia to deliver factor infusions for the treatment or prophylaxis of bleeding. Complications of CVCs in patients with haemophilia include thrombosis and infection. We report a young boy with severe haemophilia A and an inhibitor who developed disseminated Staphylococcus aureus infection most likely related to a CVC. To our knowledge, this is the first reported case of fatal sepsis secondary to a CVC in a patient with haemophilia.

摘要

中心静脉导管（CVC）常用于血友病患儿，以输注凝血因子来治疗或预防出血。血友病患者使用CVC的并发症包括血栓形成和感染。我们报告了一名患有重度甲型血友病且有凝血因子抑制物的小男孩，他发生了播散性金黄色葡萄球菌感染，很可能与CVC有关。据我们所知，这是首例报告的血友病患者因CVC继发致命性败血症的病例。