Yoshida Soichiro, Watanabe Toru, Yoshinaga Atsushi, Ohno Rena, Ishii Nobuyuki, Terao Toshiya, Hayashi Tetsuo, Yamada Takumi
Department of Urology, Saitama Medical Center, Saitama Medical School.
Hinyokika Kiyo. 2006 Jan;52(1):31-3.
Inflammatory myofibroblastic tumor (IMT) of the genitourinary tract is rare and has been classified into separate groups based on their anatomical site and postulated aetiology. Herein, we present a case of IMT of the renal pelvis. A 44-year-old man presented with gross hematuria. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) revealed a tumor of the left renal pelvis. Under the diagnosis of left renal pelvic tumor, he underwent left nephrectomy and ureterectomy. Microscopic examination revealed fascicular spindle cell proliferation in an oedematous myxoid background with an infiltrate of plasma cells. The spindle cells were strongly positive for smooth muscle actin (SMA) and vimentin, and negative for desmin and anaplastic lymphoma kinase (ALK). Diagnosis of the lesion was IMT of the renal pelvis.
泌尿生殖道炎性肌纤维母细胞瘤(IMT)较为罕见,已根据其解剖部位和推测的病因分为不同组。在此,我们报告一例肾盂炎性肌纤维母细胞瘤病例。一名44岁男性出现肉眼血尿。腹部计算机断层扫描(CT)和磁共振成像(MRI)显示左肾盂有一个肿瘤。在诊断为左肾盂肿瘤后,他接受了左肾切除术和输尿管切除术。显微镜检查显示在水肿性黏液样背景中有束状梭形细胞增生,并伴有浆细胞浸润。梭形细胞平滑肌肌动蛋白(SMA)和波形蛋白呈强阳性,结蛋白和间变性淋巴瘤激酶(ALK)呈阴性。该病变诊断为肾盂炎性肌纤维母细胞瘤。