蒙古乌兰巴托耐甲氧西林金黄色葡萄球菌的特征分析
Characterization of methicillin-resistant Staphylococcus aureus from Ulaanbaatar, Mongolia.
作者信息
Orth D, Grif K, Erdenechimeg L, Battogtokh C, Hosbayar T, Strommenger B, Cuny C, Walder G, Lass-Flörl C, Dierich M P, Witte W
机构信息
Department of Hygiene, Microbiology and Social Medicine, Innsbruck Medical University, Innsbruck, Austria.
出版信息
Eur J Clin Microbiol Infect Dis. 2006 Feb;25(2):104-7. doi: 10.1007/s10096-006-0102-6.
In order to expand current knowledge of the types of methicillin-resistant Staphylococcus aureus (MRSA) strains circulating in central Asia, six MRSA strains collected from hospitals in Ulaanbaatar, Mongolia during 2000-2002 were examined. Three strains possessed a staphylococcal cassette chromosome mec (SCCmec) element of type IV c, were sequence type (ST) 154 according to multilocus sequence typing (MLST), and contained lukS-lukF (Panton-Valentine leukocidin). Another three strains contained a SCCmec element of type III and were MLST type ST 239. Using automated ribotyping, the six MRSA strains were divided into four different EcoRI ribotypes, and two groups of isolates were distinguished by means of SmaI-macrorestriction patterns. In comparison to other countries, the incidence of MRSA in Mongolia is low.
为了拓展目前对中亚地区流行的耐甲氧西林金黄色葡萄球菌（MRSA）菌株类型的认识，对2000年至2002年期间从蒙古乌兰巴托的医院收集的6株MRSA菌株进行了检测。3株菌株拥有IV c型葡萄球菌盒式染色体mec（SCCmec）元件，根据多位点序列分型（MLST）为序列型（ST）154，并含有lukS-lukF（潘顿-瓦伦丁杀白细胞素）。另外3株菌株含有III型SCCmec元件，为MLST型ST 239。利用自动核糖体分型，这6株MRSA菌株被分为4种不同的EcoRI核糖体分型，并且通过SmaI宏观限制性酶切图谱区分出两组分离株。与其他国家相比，蒙古的MRSA发病率较低。
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