左心室长轴收缩在无症状主动脉瓣反流患者中的作用。

The role of left ventricular long-axis contraction in patients with asymptomatic aortic regurgitation.

作者信息

Paraskevaidis Ioannis A, Tsiapras Dimitrios, Kyrzopoulos Stamatis, Cokkinos Philip, Iliodromitis Efstathios K, Parissis John, Kremastinos Dimitrios T

机构信息

Second Department of Cardiology, Onassis Cardiac Surgery Center, Attiko General Hospital, Medical University, Athens, Greece.

出版信息

J Am Soc Echocardiogr. 2006 Mar;19(3):249-54. doi: 10.1016/j.echo.2005.09.019.

DOI:10.1016/j.echo.2005.09.019

PMID:16500486

Abstract

BACKGROUND

We aimed to investigate the role of long axis contraction in patients with asymptomatic chronic aorta regurgitation (AR).

METHODS

In 84 consecutive patients (48 men, mean age 55.5 +/- 13.5 years) tissue Doppler imaging was performed. During catheterization, left ventricular end-diastolic pressure (LVEDP) and end-diastolic wall stress (EDWS) were calculated.

RESULTS

The best predictor for group membership (exercise ejection fraction increase > or < of 5%) is the systolic wave maximal velocity (Sv) at the lateral mitral annulus (9 cm/s). Patients with Sv > 9 cm/s (45 patients) formed group I, while 39 patients with Sv < 9 cm/s formed group II. LVEDP and EDWS were higher in group II (15.5 +/- 1.9 mm Hg and 214.8 +/- 233.3 g/cm2) than in group I (10.3 +/- 1.7 mmHg and 111.8 +/- 40.8 g/cm2), P = .0001 and P = .01, respectively.

CONCLUSION

In patients with asymptomatic AR, the estimation of left ventricular long axis contraction at rest, can unmask a subnormal left ventricular functional status.

摘要

背景

我们旨在研究长轴收缩在无症状慢性主动脉瓣反流（AR）患者中的作用。

方法

对84例连续患者（48例男性，平均年龄55.5±13.5岁）进行组织多普勒成像检查。在导管插入过程中，计算左心室舒张末期压力（LVEDP）和舒张末期壁应力（EDWS）。

结果

用于区分分组（运动射血分数增加>或<5%）的最佳预测指标是二尖瓣环外侧的收缩波最大速度（Sv）（9 cm/s）。Sv>9 cm/s的患者（45例）为I组，而Sv<9 cm/s的39例患者为II组。II组的LVEDP和EDWS（分别为15.5±1.9 mmHg和214.8±233.3 g/cm²）高于I组（分别为10.3±1.7 mmHg和111.8±40.8 g/cm²），P值分别为0.0001和0.01。