Baxter Amy L, Fisher Randall G, Burke Bonnie L, Goldblatt Sidney S, Isaacman Daniel J, Lawson M Louise
Department of Pediatrics, Eastern Virginia Medical School, Children's Hospital of the King's Daughters, Norfolk, Virginia, USA.
Pediatrics. 2006 Mar;117(3):876-81. doi: 10.1542/peds.2005-0519.
To assess the effects of procedural techniques, local anesthetic use, and postgraduate training level on lumbar puncture (LP) success rates.
In this prospective observational study, medical students and residents ("trainees") reported techniques used for infant LPs in an urban teaching emergency department. Data on postgraduate year, patient position, draping, total and trainee numbers of attempts, local anesthetic use, and timing of stylet removal were collected. Logistic regression analysis was used to identify predictors of successful LP, with success defined as the trainee obtaining cerebrospinal fluid with <1000 red blood cells per mm3.
We collected data on 428 (72%) of 594 infant LPs performed during the study period. Of 377 performed by trainees, 279 (74%) were successful. Local anesthesia was used for 280 (74%), and 225 (60%) were performed with early stylet removal. Controlling for the total number of attempts, LPs were 3 times more likely to be successful among infants >12 weeks of age than among younger infants (odds ratio [OR]: 3.1; 95% confidence interval [CI]: 1.2-8.5). Controlling for attempts and age, LPs performed with local anesthetic were twice as likely to be successful (OR: 2.2; 95% CI: 1.04-4.6). For infants < or =12 weeks of age, early stylet removal improved success rates (OR: 2.4; 95% CI: 1.1-5.2). Position, drape use, and year of training were not significant predictors of success.
Patient age, use of local anesthetic, and trainee stylet techniques were associated with LP success rates. This offers an additional rationale for pain control. Predictors identified in this study should be considered in the training of physicians, to maximize their success with this important procedure.
评估操作技术、局部麻醉剂的使用以及研究生培训水平对腰椎穿刺(LP)成功率的影响。
在这项前瞻性观察研究中,医学生和住院医师(“实习生”)报告了在城市教学急诊科对婴儿进行腰椎穿刺时所使用的技术。收集了关于研究生年级、患者体位、铺巾、总穿刺次数和实习生穿刺次数、局部麻醉剂的使用以及针芯拔除时间的数据。采用逻辑回归分析来确定腰椎穿刺成功的预测因素,成功定义为实习生获取的脑脊液中每立方毫米红细胞数<1000个。
我们收集了研究期间进行的594例婴儿腰椎穿刺中428例(72%)的数据。在实习生进行的377例穿刺中,279例(74%)成功。280例(74%)使用了局部麻醉,225例(60%)在早期拔除了针芯。在控制总穿刺次数的情况下,年龄>12周的婴儿腰椎穿刺成功的可能性是年龄较小婴儿的3倍(比值比[OR]:3.1;95%置信区间[CI]:1.2 - 8.5)。在控制穿刺次数和年龄的情况下,使用局部麻醉进行的腰椎穿刺成功的可能性是未使用者的两倍(OR:2.2;95% CI:1.04 - 4.6)。对于年龄≤12周的婴儿,早期拔除针芯可提高成功率(OR:2.4;95% CI:1.1 - 5.2)。体位、铺巾的使用和培训年份不是成功的显著预测因素。
患者年龄、局部麻醉剂的使用以及实习生的针芯技术与腰椎穿刺成功率相关。这为疼痛控制提供了额外的理论依据。本研究中确定的预测因素在医生培训中应予以考虑,以使其在这一重要操作中获得最大成功率。