Mokhnachevskaia A I, Aksenova V A
Probl Tuberk Bolezn Legk. 2006(1):6-9.
Data on 2362 children and adolescents with chronic nonspecific lung diseases (CNLD) registered in the tuberculosis dispensaries of 5 areas of the Republic of Sakha (Yakutia) served as a clinical material for the study. Analysis of the outpatient cards of 234 children and adolescents followed up in the dispensaries for tuberculosis revealed a nonspecific bronchopulmonary disease preceding tuberculosis in 110 (47%) patients. Before falling ill with tuberculosis, 16 (15%) children had suffered from frequent colds, 41 (37%) children were found to have as many as 2-3 acute infections a year. Out of them, 12 (11%), 33 (30%), and 8 (7%) had prior pneumonia, acute bronchitis, and chronic bronchitis, respectively. This study has indicated that the late detection of a specific process in general health care facilities leads to complicated tuberculosis. This makes its treatment difficult and promotes the development of pronounced residual changes in the lung. A differential approach to examining a child or an adolescent, allowing for the aggravating factors of development of tuberculosis, and determination of the risk may significantly increase the number of patients with comorbidity, detected in due time.
萨哈共和国(雅库特)5个地区结核病防治所登记的2362例患有慢性非特异性肺部疾病(CNLD)的儿童和青少年的数据作为该研究的临床资料。对在结核病防治所接受随访的234例儿童和青少年的门诊病历分析显示,110例(47%)患者在患结核病之前存在非特异性支气管肺部疾病。在患结核病之前,16例(15%)儿童经常感冒,41例(37%)儿童每年有多达2 - 3次急性感染。其中,分别有12例(11%)、33例(30%)和8例(7%)曾患过肺炎、急性支气管炎和慢性支气管炎。该研究表明,综合医疗机构中特定疾病的延迟发现会导致结核病病情复杂。这使得治疗困难,并促使肺部出现明显的残留病变。对儿童或青少年进行检查时采用差异化方法,考虑到结核病发展的加重因素并确定风险,可能会显著增加及时发现的合并症患者数量。