未来十年的生物信息学挑战。
Bioinformatic challenges for the next decade(s).
作者信息
Eisenberg David, Marcotte Edward, McLachlan Andrew D, Pellegrini Matteo
机构信息
Howard Hughes Medical Institute UCLA-DOE Institute for Genomics and Proteomics Box 951570 UCLA, Los Angeles, CA 90095-1570, USA.
出版信息
Philos Trans R Soc Lond B Biol Sci. 2006 Mar 29;361(1467):525-7. doi: 10.1098/rstb.2005.1797.
The science of bioinformatics has developed in the wake of methods to determine the sequences of the informational macromolecules--DNAs, RNAs and proteins. But in a wider sense, the biological world depends in its every process on the transmission of information, and hence bioinformatics is the fundamental core of biology. We here give a consideration of some of the key problems of bioinformatics in the coming decade, and perhaps longer.
生物信息学这门科学是在确定信息大分子（DNA、RNA和蛋白质）序列的方法之后发展起来的。但从更广泛的意义上讲，生物界的每个过程都依赖于信息的传递，因此生物信息学是生物学的核心基础。在此，我们探讨一下未来十年甚至更长时间内生物信息学的一些关键问题。
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