Furlaneto Maria Elizabet, Garcez-Leme Luiz Eugênio
Geriatric Orthopedic Group, Institute of Orthopedics and Traumatology, Hospital das Clínicas, São Paulo University Medical School--São Paulo/SP, Brazil.
Clinics (Sao Paulo). 2006 Feb;61(1):35-40. doi: 10.1590/s1807-59322006000100007. Epub 2006 Mar 10.
To determine the incidence, prevalence, risk factors, and causes of delirium in elderly individuals with hip fractures, as well as the impact of delirium on mortality and length of hospital stay.
One hundred and three patients aged 65 and older with hip fractures were included consecutively between January 2001 and June 2002.
Delirium was diagnosed using the Confusion Assessment Method, applied within the first 24 hours after admission, and then daily. All patients underwent a global geriatric evaluation including clinical history, physical examination, laboratory tests, surgical risk evaluation, and functional and mental evaluations. Patients with delirium (cases) were compared with patients without delirium (controls).
Thirty (29.1%) patients in this sample met the criteria for delirium, with a prevalence of 16.5% (17/103) and an incidence of 12.6% (13/103). Cognitive and functional deficits had a significant association with delirium, although only cognitive deficit was revealed to be an independent risk factor after analysis with the logistic regression model. The most frequent causes of delirium were drugs and infections. The hospital stay was significantly longer for patients with delirium compared with patients in the control group (26.27 versus 14.38 days, respectively). Mortality showed a tendency to higher levels in patients with delirium during their hospital stay, although with no statistical significance.
Delirium is a frequent complication among hospitalized elderly individuals with hip fractures. It is associated with cognitive and functional deficits, and it is associated with increases the length of hospital stay and mortality.
确定髋部骨折老年患者谵妄的发病率、患病率、危险因素及病因,以及谵妄对死亡率和住院时间的影响。
2001年1月至2002年6月连续纳入103例65岁及以上的髋部骨折患者。
采用意识模糊评估法在入院后24小时内及之后每天进行谵妄诊断。所有患者均接受全面的老年评估,包括临床病史、体格检查、实验室检查、手术风险评估以及功能和心理评估。将谵妄患者(病例组)与无谵妄患者(对照组)进行比较。
本样本中有30例(29.1%)患者符合谵妄标准,患病率为16.5%(17/103),发病率为12.6%(13/103)。认知和功能缺陷与谵妄显著相关,尽管经逻辑回归模型分析后仅认知缺陷被揭示为独立危险因素。谵妄最常见的病因是药物和感染。谵妄患者的住院时间明显长于对照组患者(分别为26.27天和14.38天)。谵妄患者住院期间的死亡率有升高趋势,尽管无统计学意义。
谵妄是住院髋部骨折老年患者常见的并发症。它与认知和功能缺陷相关,且与住院时间延长和死亡率增加有关。