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[突尼斯流感嗜血杆菌脑膜炎的流行病学]

[Epidemiology of Haemophilus influenzae meningitis in Tunisia].

作者信息

Soltani M S, Bchir A, Amri F, Gueddiche N, Sfar T, Sahloul S, Garbouj M

机构信息

C.H.U. de Monastir, Tunisie.

出版信息

East Mediterr Health J. 2005 Jan-Mar;11(1-2):14-27.

Abstract

The incidence of Haemophilus influenzae b meningitis (Hib) in children < 5 years in Tunisia was studied through a surveillance system set up in June 2000 and followed for 14 months. Population-based surveillance began in 3 governorates and sentinel surveillance in 2. Children < 5 years suspected of meningitis had lumbar puncture, macroscopic exam, blood count, chemical analysis and culture carried out. In the 14 months, 80 cases of meningitis were recorded. From the population-based surveillance most cases were children < 1 year (73.6%) and boys (64%). H. influenzae was isolated in 38% of cases, pneumococci in 13% and meningococci in 7%. The incidence of confirmed Hib was 14.4/100 000 children. The estimated cost of identifying and treating Hib meningitis and its complications was greater than the cost of vaccine introduction. Based this study, the Ministry of Health has decided to introduce Hib vaccination.

摘要

通过2000年6月建立并持续14个月的监测系统,对突尼斯5岁以下儿童中B型流感嗜血杆菌脑膜炎(Hib)的发病率进行了研究。基于人群的监测始于3个省份,哨点监测始于2个省份。对疑似脑膜炎的5岁以下儿童进行了腰椎穿刺、肉眼检查、血细胞计数、化学分析和培养。在这14个月中,记录了80例脑膜炎病例。在基于人群的监测中,大多数病例为1岁以下儿童(73.6%)且为男孩(64%)。38%的病例分离出了流感嗜血杆菌,13%分离出肺炎球菌,7%分离出脑膜炎球菌。确诊的Hib发病率为14.4/10万儿童。识别和治疗Hib脑膜炎及其并发症的估计成本高于引入疫苗的成本。基于这项研究,卫生部已决定引入Hib疫苗接种。

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