Demirci Fikret, Savaş M Cemil, Kepkep Necip, Okan Vahap, Yilmaz Mehmet, Büyükberber Mehmet, Gülşen M Taner
Division of Gastroenterology, School and Hospital of Medicine, Gaziantep University, Gaziantep, Turkey.
Turk J Gastroenterol. 2005 Dec;16(4):224-7.
Plummer-Vinson syndrome is known as the association of postcricoid dysphagia, upper esophageal web, and iron deficiency anemia. Although correction of iron deficiency may result in resolution of dysphagia and sometimes disappearance of the webs, dilation therapy is usually necessary to remove webs and relieve dysphagia. We report two cases of Plummer-Vinson syndrome. Both patients presented with significant and longstanding dysphagia, sideropenia, glossitis and koilonychia. Our two patients had occasional choking and aspiration episodes at eating and endoscope did not pass through at the level of the upper esophagus. Patients' esophagograms revealed the presence of webs in part of the post-cricoid region. Both patients were treated with esophageal bougienage or balloon dilation, and iron supplementation. The patients were examined periodically for two years after the initial treatment and found to be in good general condition.
普卢默-文森综合征以环状软骨后吞咽困难、食管上段蹼和缺铁性贫血相关联为特征。尽管纠正缺铁可能会使吞咽困难缓解,且有时食管蹼会消失,但通常需要进行扩张治疗以去除食管蹼并缓解吞咽困难。我们报告两例普卢默-文森综合征病例。两名患者均有严重且长期的吞咽困难、缺铁、舌炎和匙状甲。我们的两名患者进食时偶尔有呛咳和误吸发作,并且内镜无法通过食管上段。患者的食管造影显示环状软骨后区域部分存在食管蹼。两名患者均接受了食管探条扩张术或球囊扩张术以及铁剂补充治疗。在初始治疗后对患者进行了为期两年的定期检查,发现他们的总体状况良好。