Bürk Gisela, Höbel Werner, Richt Anita
Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Rückstandsanalytik, Zentrallabor Chemie, Oberschleissheim, Germany.
Mol Nutr Food Res. 2006 Apr;50(4-5):437-42. doi: 10.1002/mnfr.200500192.
The danger of ergot alkaloids has been well known for centuries. The origin and toxicology of these compounds have been clarified and flour mills assure us that they have mastered the problem technologically. Nevertheless, one can find food products with sometimes relatively high contents of these toxic alkaloids. Here we report on our experiences and results of an LC-MS/MS-method which we have developed to determine ergot alkaloids and which was applied to commercial products during the past two years.
几个世纪以来,麦角生物碱的危险性已广为人知。这些化合物的来源和毒理学已得到阐明,面粉厂也向我们保证,他们已从技术上攻克了这一问题。然而,人们有时仍能发现某些食品中这些有毒生物碱的含量相对较高。在此,我们报告我们在开发用于测定麦角生物碱的液相色谱 - 串联质谱法(LC-MS/MS)方面的经验和结果,该方法在过去两年已应用于商业产品检测。