Koktzoglou Ioannis, Chung Yiu-Cho, Mani Venkatesh, Carroll Timothy J, Morasch Mark D, Mizsei Gabor, Simonetti Orlando P, Fayad Zahi A, Li Debiao
Department of Radiology, Northwestern University, Chicago, Illinois 60611, USA.
J Magn Reson Imaging. 2006 May;23(5):699-705. doi: 10.1002/jmri.20563.
To compare two multislice turbo spin-echo (TSE) carotid artery wall imaging techniques at 1.5 T and 3.0 T, and to investigate the feasibility of higher spatial resolution carotid artery wall imaging at 3.0 T.
Multislice proton density-weighted (PDW), T2-weighted (T2W), and T1-weighted (T1W) inflow/outflow saturation band (IOSB) and rapid extended coverage double inversion-recovery (REX-DIR) TSE carotid artery wall imaging was performed on six healthy volunteers at 1.5 T and 3.0 T using time-, coverage-, and spatial resolution-matched (0.47 x 0.47 x 3 mm3) imaging protocols. To investigate whether improved signal-to-noise ratio (SNR) at 3.0 T could allow for improved spatial resolution, higher spatial resolution imaging (0.31 x 0.31 x 3 mm3) was performed at 3.0 T. Carotid artery wall SNR, carotid lumen SNR, and wall-lumen contrast-to-noise ratio (CNR) were measured.
Signal gain at 3.0 T relative to 1.5 T was observed for carotid artery wall SNR (223%) and wall-lumen CNR (255%) in all acquisitions (P < 0.025). IOSB and REX-DIR images were found to have different levels of SNR and CNR (P < 0.05) with IOSB values observed to be larger. Normalized to a common imaging time, the higher spatial resolution imaging at 3.0 T and the lower spatial resolution imaging at 1.5 T provided similar levels of wall-lumen CNR (P = NS).
Multislice carotid wall imaging at 3.0 T with IOSB and REX-DIR benefits from improved SNR and CNR relative to 1.5 T, and allows for higher spatial resolution carotid artery wall imaging.
比较1.5 T和3.0 T下的两种多层涡轮自旋回波(TSE)颈动脉壁成像技术,并研究在3.0 T下进行更高空间分辨率颈动脉壁成像的可行性。
对6名健康志愿者在1.5 T和3.0 T下使用时间、覆盖范围和空间分辨率匹配(0.47×0.47×3 mm3)的成像方案进行多层质子密度加权(PDW)、T2加权(T2W)以及T1加权(T1W)流入/流出饱和带(IOSB)和快速扩展覆盖双反转恢复(REX-DIR)TSE颈动脉壁成像。为研究3.0 T下改善的信噪比(SNR)是否能实现更高的空间分辨率,在3.0 T下进行了更高空间分辨率成像(0.31×0.31×3 mm3)。测量了颈动脉壁SNR、颈动脉腔SNR以及壁腔对比噪声比(CNR)。
在所有采集图像中,相对于1.5 T,3.0 T下颈动脉壁SNR(223%)和壁腔CNR(255%)均观察到信号增益(P < 0.025)。发现IOSB和REX-DIR图像具有不同水平的SNR和CNR(P < 0.05),且观察到IOSB值更大。以相同成像时间进行归一化后,3.0 T下的更高空间分辨率成像和1.5 T下的较低空间分辨率成像提供了相似水平的壁腔CNR(P = 无显著性差异)。
与1.5 T相比,采用IOSB和REX-DIR的3.0 T多层颈动脉壁成像受益于改善的SNR和CNR,并允许进行更高空间分辨率的颈动脉壁成像。