Reichman Nancy E, Teitler Julien O
Department of Pediatrics, Robert Wood Johnson Medical School, 97 Paterson Street, Room 435, New Brunswick, NJ 08903, USA.
Am J Public Health. 2006 May;96(5):862-6. doi: 10.2105/AJPH.2005.066324. Epub 2006 Mar 29.
We examined associations between paternal age and low birth-weight in the US urban population.
Using a population-based sample of 4621 births, we used multiple logistic regression analysis to estimate associations between paternal age and low birthweight, controlling for maternal age, other demographic factors, and the child's gender.
When the child's gender and the mother's race/ethnicity, birthplace, parity, marital status, and health insurance type were controlled, teenaged fathers were 20% less likely and fathers older than 34 years were 90% more likely than fathers aged 20 to 34 years to have low-birthweight babies. The associations were significant when maternal age was also controlled. No racial/ethnic differences in associations between paternal age and low birthweight were found.
We identified paternal age as an independent risk factor for low birthweight in the US urban population, suggesting that more attention needs to be paid to paternal influences on birth outcomes and to the interactive effects of urban environments and individual risk factors on health.
我们研究了美国城市人口中父亲年龄与低体重出生之间的关联。
利用基于人群的4621例出生样本,我们采用多元逻辑回归分析来估计父亲年龄与低体重出生之间的关联,并控制母亲年龄、其他人口统计学因素以及孩子的性别。
在控制了孩子的性别以及母亲的种族/民族、出生地、产次、婚姻状况和医疗保险类型后,青少年父亲生出低体重婴儿的可能性比20至34岁的父亲低20%,34岁以上的父亲生出低体重婴儿的可能性比20至34岁的父亲高90%。在控制母亲年龄后,这种关联仍然显著。未发现父亲年龄与低体重出生之间的关联存在种族/民族差异。
我们确定父亲年龄是美国城市人口中低体重出生的一个独立风险因素,这表明需要更多地关注父亲对出生结局的影响以及城市环境和个体风险因素对健康的交互作用。