光疗法对季节性情感障碍患者、非季节性情感障碍患者及健康对照者3H-丙咪嗪结合位点的影响。

Effect of phototherapy on 3H-imipramine binding sites in patients with SAD, non-SAD and in healthy controls.

作者信息

Szádóczky E, Falus A, Németh A, Teszéri G, Moussong-Kovács E

机构信息

Postgraduate Medical School Department of Psychiatry and Clinical Psychology, National Institute for Nervous and Mental Diseases, Budapest, Hungary.

出版信息

J Affect Disord. 1991 Aug;22(4):179-84. doi: 10.1016/0165-0327(91)90063-x.

DOI:10.1016/0165-0327(91)90063-x

PMID:1658102

Abstract

The effect of incandescent light treatment on the density of 3H-imipramine binding sites (Bmax) was investigated in 17 patients with seasonal affective disorder, in eight patients with non-seasonal depression and in six healthy volunteers. A significant increase in mean Bmax value parallel to a marked improvement of the depressive symptoms was found only in patients with SAD. No effect was observed either on mean Bmax value or on clinical symptoms in patients with non-SAD and on mean Bmax value in healthy volunteers.

摘要

在17例季节性情感障碍患者、8例非季节性抑郁症患者和6名健康志愿者中，研究了白炽灯治疗对3H-丙咪嗪结合位点密度（Bmax）的影响。仅在季节性情感障碍患者中发现平均Bmax值显著增加，同时抑郁症状明显改善。在非季节性情感障碍患者中，未观察到对平均Bmax值或临床症状有影响；在健康志愿者中，也未观察到对平均Bmax值有影响。