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[Butyrylcholinesterase deficiency: how to analyse the cholinesterase activity in small children?].

作者信息

Lejus C, Delaroche O, Trille E, Blanloeil Y, Pinaud M

机构信息

Service d'Anesthésie et de Réanimation Chirurgicale, Hôtel-Dieu-Hôpital Mère-Enfant, CHU de Nantes, 44093 Nantes Cedex 01, France.

出版信息

Ann Fr Anesth Reanim. 2006 Jun;25(6):657-60. doi: 10.1016/j.annfar.2006.02.009. Epub 2006 Apr 11.

Abstract

We report the case of a prolonged neuromuscular blockade in an 18-month-old age girl following administration of a usual dose of succinylcholine. The diagnosis was highly suggested by the clinical history while cholinesterase activity was included in adult normal values but below values of a personal series of 41 small children. The familial analysis of dibucaine and fluoride number confirmed the hypothesis of an atypical variant (AA phenotype). The cholinesterase activity is higher in small children than in adult and has to be analysed according to the age.

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