Yildizeli B, Laçin T, Batirel H F, Yüksel M
Department of Thoracic Surgery, Faculty of Medicine, Marmara University Hospital, Acibadem, Istanbul, Turkey.
J Vasc Access. 2004 Oct-Dec;5(4):174-8. doi: 10.1177/112972980400500407.
Although prolonged venous access devices (PVADs) are used in case prolonged intravenous therapy is required, implantation and use of these devices is associated with complications. The purpose of this study was to evaluate perioperative and long-term complications associated with PVADs and the management of these complications.
A retrospective review was undertaken of 225 PVADs implanted in 217 patients from February 1993 to June 2004. This included 144 single-lumen port infusion systems, 49 single-lumen Hickman catheters and 32 double-lumen Groshong catheters. The PVADs were inserted using either the percutaneous Seldinger method (n=183) or cutdown access to the subclavian vein (n=42). Indications for placement were as follows: chemotherapy in 66.2% of patients, drug-infusion treatment in 31.6% of patients and total parenteral nutrition in 2.2% of patients.
Perioperative complications occurred in 13 patients (5.7%): catheter malposition in seven patients (3.1%), pneumothorax in three patients (1.3%), hemorrhage in two patients (0.9%) and catheter embolization in one patient (0.4%). Long-term complications appeared in 15 patients (6.6%): infection in five patients (2.2%), thrombosis in three patients (1.3%), extravasation in three patients (1.3%), and catheter fracture in four patients (1.8%). The fractured fragments were removed by the Amplatz snare device. In 10 patients (4.4%) only were PVADs removed prior to completion of the intended therapy. Indications for removal were catheter infection in five patients (2.2%) and catheter fracture in five patients (2.2%).
PVAD implantation is associated with some risk of serious perioperative and long-term complications. Care of the catheter and the patient should be maintained with the proper and immediate evaluation of the perioperative and long-term complications.
尽管在需要长期静脉治疗时会使用长期静脉通路装置(PVADs),但这些装置的植入和使用会引发并发症。本研究的目的是评估与PVADs相关的围手术期和长期并发症以及这些并发症的处理。
对1993年2月至2004年6月期间217例患者植入的225个PVADs进行回顾性研究。其中包括144个单腔端口输液系统、49个单腔Hickman导管和32个双腔Groshong导管。PVADs采用经皮Seldinger法插入183例(n = 183)或切开进入锁骨下静脉42例(n = 42)。放置的适应证如下:66.2%的患者用于化疗,31.6%的患者用于药物输注治疗,2.2%的患者用于全胃肠外营养。
13例患者(5.7%)发生围手术期并发症:7例患者(3.1%)导管位置不当,3例患者(1.3%)气胸,2例患者(0.9%)出血,1例患者(0.4%)导管栓塞。15例患者(6.6%)出现长期并发症:5例患者(2.2%)感染,3例患者(1.3%)血栓形成,3例患者(1.3%)外渗,4例患者(1.8%)导管断裂。断裂碎片通过Amplatz圈套器取出。仅10例患者(4.4%)在预定治疗完成前拔除了PVADs。拔除的适应证为5例患者(2.2%)导管感染和5例患者(2.2%)导管断裂。
PVAD植入与一些严重的围手术期和长期并发症风险相关。应通过对围手术期和长期并发症进行适当和及时的评估来维持对导管和患者的护理。